Synthesis and Biological Activity of N'-(substituted pyrimidin-2-yl)- N-chrysanthemoylthiourea Derivatives

Abstract

Five new N′-(substituted pyrimidin-2-yl)-N-chrysanthemoylthiourea derivatives and three new N′-(substituted pyrimidin-2-yl)-N-dichlorochrysanthemoylthiourea derivatives have been synthesized and characterized. The structures of these compounds were conformed by ¹H NMR, IR spectra and elemental analysis. The preliminary biological tests showed that some of these target compounds have excellent biological activity.

Key words: N′-(substituted pyrimidin-2-yl)-N-chrysanthemoylthiourea, synthesis, biological activity, N′-(substituted pyrimidin-2-yl)-N- dichlorochrysanthemoylthiourea

Cite this article

XU Dong-Fang,LI Jing-Zhi,GUO Yan-Ling,KE Shao-Yong,XUE Si-Jia*. Synthesis and Biological Activity of N'-(substituted pyrimidin-2-yl)- N-chrysanthemoylthiourea Derivatives[J]. Chin. J. Org. Chem., 2005, 25(9): 1053-1056.

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