Chin. J. Org. Chem. ›› 2008, Vol. 28 ›› Issue (11): 2016-2019. Previous Articles     Next Articles

Reports

新型薁类-1-酰腙化合物的合成及抗菌活性研究

王道林* ; 徐 姣; 韩 珊; 谷 峥   

  1. (渤海大学化学化工学院 辽宁省应用化学重点实验室 锦州 121003)
  • 收稿日期:2007-12-06 修回日期:2008-05-04 发布日期:2008-11-18
  • 通讯作者: 王道林

Synthesis of Some New Hydrazone Compounds Containing Azulene and Their Antibacterial Activity

WANG, Dao-Lin* ; XU, Jiao; HAN, Shan ; GU, Zheng   

  1. (Liaoning Key Laboratory of Applied Chemistry, College of Chemistry and Chemical Engineering,
    Bohai University, Jinzhou 121003)
  • Received:2007-12-06 Revised:2008-05-04 Published:2008-11-18
  • Contact: WANG, Dao-Lin

In order to synthesize and search new bioactive substance containing azulene, some new hydrazone compounds were synthesized by the reaction of methyl azulene-1-carboxylate with hydrazine and con-densation with arylaldehydes or ketones. All of above compounds have been confirmed by 1H NMR, IR spectra and elemental analysis, and the bioassay result indicated that some of the title compounds had rela-tively antibacterial activity.

Key words: hydrazine, azulene, hydrazone, antibacterial activity, synthesis