Chin. J. Org. Chem. ›› 2010, Vol. 30 ›› Issue (08): 1250-1254. Previous Articles     Next Articles

Notes

苄基三甲基三溴化铵作用下合成6-溴代喹啉类化合物

武利强*,闫福林,杨利敏,杨春广   

  1. (新乡医学院药学院 新乡 453003)
  • 收稿日期:2009-11-15 修回日期:2010-03-24 发布日期:2010-04-09
  • 通讯作者: 武利强 E-mail:wliq1974@sohu.com

Synthesis of 6-Bromoquinolines Using Benzyltrimethyl- ammonium Tribromide

WU Li-Qiang, YAN Fu-Lin, YANG Li-Min, YANG Chun-Guang   

  1. (School of Pharmacy, Xinxiang Medical University, Xinxiang 453003)
  • Received:2009-11-15 Revised:2010-03-24 Published:2010-04-09

A series of 6-bromoquinolines were synthesized in high yields by reaction of 2-aminobenzo- phenone with α-methylene carbonyl compounds in the presence of benzyltrimethylammonium tribromide in CH3CN at room temperature. All products were characterized by 1H NMR, 13C NMR spectra and elemental analysis.

Key words: 6-bromoquinolines, benzyltrimethylammonium tribromide, friedlander reation, synthesis