Synthesis and Biological Activities of N-Pyridyl(thiazolyl) Methyloxyphenyl-N-arylacyl Urea Derivatives

Chin. J. Org. Chem. ›› 2011, Vol. 31 ›› Issue (04): 582-585. Previous Articles Next Articles

Notes

N-吡啶(噻唑)甲氧苯基-N-芳酰基脲衍生物的合成与生物活性

梁英，张志刚，魏三，杨自文*

(湖北省农业科学院湖北省生物农药工程研究中心绿色化学与合成研究室武汉 430064)

收稿日期:2010-06-28 修回日期:2010-09-25 发布日期:2010-12-06
通讯作者: 梁英 E-mail:ly.liang8@gmail.com

Synthesis and Biological Activities of N-Pyridyl(thiazolyl) Methyloxyphenyl-N-arylacyl Urea Derivatives

LIANG Ying, ZHANG Zhi-Gang, WEI San, YANG Zi-Wen

(Laboratory of Green Chemistry & Synthesis, Hubei Biopesticide Engineering Research Center, Hubei Academy of Agricultural Science, Wuhan 430064)

Received:2010-06-28 Revised:2010-09-25 Published:2010-12-06
Contact: LIANG Ying E-mail:ly.liang8@gmail.com

Abstract

Eight new N-pyridyl(thiazolyl) methyloxyphenyl-N-arylacyl urea derivatives were synthesized by the nucleophilic addition reaction of pyridyl(thiazolyl) methyloxy aniline with arylacyl isocyanates. Their structures were confirmed by ¹H NMR, IR spectra and elemental analysis. Preliminary biological tests indicated that these compounds exhibited obvious insecticidal activity, especially, compound 5d showed 100% inhibitory activity against Heliothis armigera and Plutella xylostella at 100 mg/L.

Key words: benzoylurea, synthesis, insecticidal activity

Cite this article

LIANG Ying, ZHANG Zhi-Gang, WEI San, YANG Zi-Wen. Synthesis and Biological Activities of N-Pyridyl(thiazolyl) Methyloxyphenyl-N-arylacyl Urea Derivatives[J]. Chin. J. Org. Chem., 2011, 31(04): 582-585.

Export EndNote|Reference Manager|ProCite|BibTeX|RefWorks

[1]	Fakai Zou, Nengzhong Wang, Hui Yao, Hui Wang, Mingguo Liu, Nianyu Huang. Regio- and Stereo-selective Synthesis of 1β-/3R-Aryl Thiosugar [J]. Chinese Journal of Organic Chemistry, 2024, 44(2): 593-604.
[2]	Luyao Li, Zhongwen He, Zhenguo Zhang, Zhenhua Jia, Teck-Peng Loh. Application of Triaryl Carbenium in Organic Synthesis [J]. Chinese Journal of Organic Chemistry, 2024, 44(2): 421-437.
[3]	Qinggang Mei, Qinghan Li. Recent Progress of Visible Light-Induced the Synthesis of C(3) (Hetero)arylthio Indole Compounds [J]. Chinese Journal of Organic Chemistry, 2024, 44(2): 398-408.
[4]	Penghui Li, Qingyang Xie, Fuxian Wan, Yuanhong Zhang, Lin Jiang. Synthesis and Fungicidal Activity of Novel Substituted Pyrimidine-5-carboxamides Bearing Cyclopropyl Moiety [J]. Chinese Journal of Organic Chemistry, 2024, 44(2): 650-656.
[5]	Weiqing Yang, Yanbing Ge, Yuanyuan Chen, Ping Liu, Haiyan Fu, Menglin Ma. Design and Synthesis of Fluorescent 1,8-Napthalimide Derivatives and Their Identification of Cysteine [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 180-194.
[6]	Shihang Yu, Jiawei Liu, Biyu An, Qinghua Bian, Min Wang, Jiangchun Zhong. Asymmetric Synthesis of the Contact Sex Pheromone of Neoclytus acuminatus acuminatus (Fabricius) [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 301-308.
[7]	Qianfan Zhao, Yongzheng Chen, Shiming Zhang. Application and Mechanism Study of Carbon-Based Metal-Free Catalysts in Organic Synthesis [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 137-147.
[8]	Shan Chen, Zhilin Chen, Qiong Hu, Yanshuang Meng, Yue Huang, Pingfang Tao, Liru Lu, Guobao Huang. Recognition of Bis-thiourea Tweezers to Neutral Molecules in Non-Polar Solvent [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 277-281.
[9]	Huakun Wang, Xiaolong Ren, Yining Xuan. Study of the Halide Salt Catalyzed [3＋2] Cycloaddition of α,β-Epoxy Carboxylate with Isocyanate [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 251-258.
[10]	Yukun Jin, Baoyi Ren, Fushun Liang. Visible Light-Mediated Selective C—F Bond Cleavage of Trifluoromethyl Groups and Its Application in Synthesizing gem-Difluoro-Containing Compounds [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 85-110.
[11]	Cuiyun Ma, Hailan Luo, Fuhua Zhang, Dan Guo, Shuxing Chen, Fei Wang. Green Biosynthesis, Photophysical Properties and Application of 3-Pyrrolyl BODIPY [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 216-223.
[12]	Bozhen Wang, Jie Zhang, Chunhui Nian, Mingming Jin, Miaomiao Kong, Wulan Li, Wenfei He, Jianzhang Wu. Synthesis and Antitumor Activity of 3,4-Dichlorophenyl Amides [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 232-241.
[13]	Ruixia Cao, Yuping Jia. Synthesis and Biological Activity of Novel Pyrrolo[2,3-d]pyrimidine Derivatives Containing Coumarin [J]. Chinese Journal of Organic Chemistry, 2023, 43(9): 3304-3311.
[14]	Huanqing Li, Zhaohua Chen, Zujia Chen, Qiwen Qiu, Youcai Zhang, Sihong Chen, Zhaoyang Wang. Research Progress in Mercury Ion Fluorescence Probes Based on Organic Small Molecules [J]. Chinese Journal of Organic Chemistry, 2023, 43(9): 3067-3077.
[15]	Ran Zhou, Chunmei Yuan, Tao Zhang, Piao Mao, Yi Liu, Kaini Meng, Hui Xin, Wei Xue. Design, Synthesis and Bioactivity of Chalcone Derivative Containing Quinazolinone [J]. Chinese Journal of Organic Chemistry, 2023, 43(9): 3196-3209.

N-吡啶(噻唑)甲氧苯基-N-芳酰基脲衍生物的合成与生物活性

Synthesis and Biological Activities of N-Pyridyl(thiazolyl) Methyloxyphenyl-N-arylacyl Urea Derivatives

PDF

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments