Synthesis and Insecticidal Activities of Pyrazole-heterocyclic Dia-mides

Chin. J. Org. Chem. ›› 2011, Vol. 31 ›› Issue (9): 1510-1515. Previous Articles Next Articles

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含吡唑杂环二酰胺类化合物的合成与杀虫活性研究

葛前建¹，陈列忠²，杜晓华*^,1

(¹浙江工业大学催化加氢研究中心杭州 310014)
(²浙江省农科院杭州 310021)

收稿日期:2010-12-29 修回日期:2011-03-23 发布日期:2011-04-28
通讯作者: 杜晓华 E-mail:duxiaohua@zjut.edu.cn

Synthesis and Insecticidal Activities of Pyrazole-heterocyclic Dia-mides

Ge Qianjian¹ Chen Liezhong² Du Xiao-hua*^,1

(¹Catalytic Hydrogenation Research Center, Zhejiang University of Technology, Hangzhou 310014)
(²Zhejiang Academy of Agricultural Sciences, Hangzhou 310021)

Received:2010-12-29 Revised:2011-03-23 Published:2011-04-28

16 novel pyrazole-heterocyclic diamides were synthesized according to the principle of combination of bioactive substructures, and their structures were characterized by IR, ¹H NMR and HRMS techniques. The crystal structure of 3h was determined by X-ray diffraction analysis. Preliminary bioassays showed that some compounds had lethal activities against Mythimna sepatara and Aphis medicaginis at the dosage of 500 mg/L|some of the compounds had lethal activities against the larvae of Ectropis oblique hypulina Wehrli at the dosage of 100 mg/L, the treated insects appeared to have anti-feeding effect.

Key words: bioactive substructure, diamides, ryanodine receptor activator, synthesis, insecticidal activity

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GE Qian-Jian, CHEN Lie-Zhong, DU Xiao-Hua. Synthesis and Insecticidal Activities of Pyrazole-heterocyclic Dia-mides[J]. Chin. J. Org. Chem., 2011, 31(9): 1510-1515.

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含吡唑杂环二酰胺类化合物的合成与杀虫活性研究

Synthesis and Insecticidal Activities of Pyrazole-heterocyclic Dia-mides

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