Synthesis and Plant Growth Regulating Activities of iso-Abscisic Acid

doi:10.6023/cjoc201402034

Chin. J. Org. Chem. ›› 2014, Vol. 34 ›› Issue (8): 1692-1698.DOI: 10.6023/cjoc201402034 Previous Articles Next Articles

Notes

异脱落酸的合成及植物生长调节活性

韩小强, 万川, 杨冬燕, 杜士杰, 袁小勇, 肖玉梅, 覃兆海

中国农业大学理学院应化系北京 100193

收稿日期:2014-02-27 修回日期:2014-03-24 发布日期:2014-04-10
通讯作者: 覃兆海 E-mail:qinzhaohai@263.net
基金资助:
国家自然科学基金（No.20972184）和国家高技术研究发展计划（No.2011AA10A206）资助项目

Synthesis and Plant Growth Regulating Activities of iso-Abscisic Acid

Han Xiaoqiang, Wan Chuan, Yang Dongyan, Du Shijie, Yuan Xiaoyong, Xiao Yumei, Qin Zhaohai

Department of Applied Chemistry, China Agricultural University, Beijing 100193

Received:2014-02-27 Revised:2014-03-24 Published:2014-04-10
Supported by:
Project supported by the National Natural Science Foundation of China (No. 20972184) and the National Hi-Tech Research and Development Program of China (No. 2011AA10A206).

1. Synthesis and Plant Growth Regulating Activities of iso-Abscisic Acid.PDF(1951KB)

Abstract

The iso-abscisic acid (iso-ABA) analogs 11, 12, 13 and 14 were synthesized via regioselective addition of acetylides to enediones, selective reduction, Dess-Martin oxidation and Lindgren oxidation. The racemic mixtures 11 were resolved by chiral HPLC. These iso-ABA analogs and ABA were tested for their inhibitory activity in four bioassays. (+)-iso-ABA 11 exhibited high ABA-like activity, including the ability to effectively inhibit seed germination and seedling growth. The analogs 12, 13, 14 were also prepared and biological activities were investigated. Comparison of four bioassays, the iso-abscisic acid analogs had better activity in lettuce seed germination.

Key words: phytohormone, iso-abscisic acid analogs, synthesis, biological activities

Cite this article

Han Xiaoqiang, Wan Chuan, Yang Dongyan, Du Shijie, Yuan Xiaoyong, Xiao Yumei, Qin Zhaohai. Synthesis and Plant Growth Regulating Activities of iso-Abscisic Acid[J]. Chin. J. Org. Chem., 2014, 34(8): 1692-1698.

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异脱落酸的合成及植物生长调节活性

Synthesis and Plant Growth Regulating Activities of iso-Abscisic Acid

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