Synthesis and Herbicidal Activities of Novel Ethyl 2-(4-(Pyridin-2-yl-oxy)phenyl-amino)propanoates/acetates

doi:10.6023/cjoc201608018

Chin. J. Org. Chem. ›› 2017, Vol. 37 ›› Issue (2): 526-532.DOI: 10.6023/cjoc201608018 Previous Articles Next Articles

NOTE

新型吡啶氧基苯胺基丙酸/乙酸乙酯的合成以及除草活性研究

徐志红^a, 张涛^b, 王少康^b, 李俊凯^a

a 长江大学主要粮食作物产业化湖北省协同创新中心荆州 434205;
b 长江大学农学院荆州 434205

收稿日期:2016-08-23 修回日期:2016-09-06 发布日期:2016-10-09
通讯作者: 李俊凯 E-mail:junkaili@sina.com
基金资助:
国家自然科学基金（No.31301976）和主要粮食作物产业化湖北省协同创新中心开放基金资助项目.

Synthesis and Herbicidal Activities of Novel Ethyl 2-(4-(Pyridin-2-yl-oxy)phenyl-amino)propanoates/acetates

Xu Zhihong^a, Zhang Tao^b, Wang Shaokang^b, Li Junkai^a

a Hubei Collaborative Innovation Center for Grain Industry, Yangtze University, Jingzhou 434205;
b Agricutural College, Yangtze University, Jingzhou 434205

Received:2016-08-23 Revised:2016-09-06 Published:2016-10-09
Supported by:
Project supported by the National Natural Science Foundation of China and the Open Fund for Hubei Collaborative Innovation Center for Grain Industry.

1. Synthesis and Herbicidal Activities of Novel Ethyl 2-(4-(Pyridin-2-yl-oxy)phenyl-amino)propanoates/acetates.PDF(1530KB)

Abstract

Aryloxyphenoxypropionates (APPs) are a class of herbicides targeting on acetyl-coenzyme A carboxylase (ACCase) in monocot chloroplast. The article presents synthesis of twenty three novel ethyl 2-(4-(pyridin-2-yl-oxy)phenylamino)-propanoates/acetates, and their structures were characterized by ¹H NMR, HRMS and X-ray single-crystal diffraction. The herbicidal activities on barnyard grass and rape of the novel compounds were evaluated. Ethyl 2-(4-(5-nitropyridin-2-yloxy)-phenylamino)propanoate (B5) showed almost the same level of herbicidal activity on barnyard grass as commercial herbicide fluazifop-methyl which could become a potential lead compound on weeds.

Key words: ethyl 2-(4-(pyridin-2-yl-oxy)phenylamino)propanoate/acetates, synthesis, herbicidal activity, acetyl-CoA carboxylase

Cite this article

Xu Zhihong, Zhang Tao, Wang Shaokang, Li Junkai. Synthesis and Herbicidal Activities of Novel Ethyl 2-(4-(Pyridin-2-yl-oxy)phenyl-amino)propanoates/acetates[J]. Chin. J. Org. Chem., 2017, 37(2): 526-532.

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新型吡啶氧基苯胺基丙酸/乙酸乙酯的合成以及除草活性研究

Synthesis and Herbicidal Activities of Novel Ethyl 2-(4-(Pyridin-2-yl-oxy)phenyl-amino)propanoates/acetates

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