Research Progress on the Synthesis of Morphine Alkaloids

doi:10.6023/cjoc201702048

Chin. J. Org. Chem. ›› 2017, Vol. 37 ›› Issue (7): 1629-1652.DOI: 10.6023/cjoc201702048 Previous Articles Next Articles

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吗啡类生物碱的合成研究进展

李其林^a,b, 张洪彬^b

a. 云南省地震局昆明 650224;
b. 云南大学教育部自然资源药物化学重点实验室昆明 650091

收稿日期:2017-01-28 修回日期:2017-03-22 发布日期:2017-04-13
通讯作者: 张洪彬 E-mail:zhanghb@ynu.edu.cn
基金资助:
长江学者和创新团队发展计划（No.IRT13095）、国家自然科学基金（Nos.20925205，21332007）资助项目.

Research Progress on the Synthesis of Morphine Alkaloids

Li Qilin^a,b, Zhang Hongbin^b

a. Earthquake Administration of Yunnan Province, Kunming 650224;
b. Key Laboratory of Medicinal Chemistry for Natural Resource Ministry of Education, Yunnan University, Kunming 650091

Received:2017-01-28 Revised:2017-03-22 Published:2017-04-13
Contact: 10.6023/cjoc201702048 E-mail:zhanghb@ynu.edu.cn
Supported by:
Project supported by the Program for Changjiang Scholars and Innovative Research Team in University (No.IRT13095),and the National Natural Science Foundation of China (Nos.20925205,21332007).

The morphine alkaloids constitute a class of structurally related natural products isolated from opium poppy, Papaver somniferum. The synthesis of morphine and its derivatives has attracted the attention of many generations of synthetic chemists due to their highly challenging molecular architecture and biological activities. Progresses toward the synthesis of the morphine alkaloids are reviewed in terms of chronological order.

Key words: morphine, morphine alkaloids, synthesis

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Li Qilin, Zhang Hongbin. Research Progress on the Synthesis of Morphine Alkaloids[J]. Chin. J. Org. Chem., 2017, 37(7): 1629-1652.

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吗啡类生物碱的合成研究进展

Research Progress on the Synthesis of Morphine Alkaloids

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