Progress in C—N Bond Formation Involving C(sp2)—H Bond through Transition-Metal-Free Radical Reactions

doi:10.6023/cjoc201909032

Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (3): 589-597.DOI: 10.6023/cjoc201909032 Previous Articles Next Articles

无过渡金属体系下C (sp²)—H键的自由基反应构建C—N键研究进展

吴燕^a,c, 陈锦杨^a,c, 李强^b, 魏文廷^c

a 长江师范学院化学化工学院重庆 408000;
b 聊城大学化学化工学院山东聊城 252059;
c 宁波大学材料科学与化学工程学院浙江宁波 315211

收稿日期:2019-09-22 修回日期:2019-10-26 发布日期:2020-04-02
通讯作者: 陈锦杨, 魏文廷 E-mail:chenjinyang@hnu.edu.cn;weiwenting@nbu.edu.cn
基金资助:
重庆市基础前沿研究（Nos.Cstc2018jcyjAX0721，Cstc2018jcyjAX0051）、长江师范学院青年人才成长计划（No.2018QNRC11）、重庆市教育委员会（No.KJQN201801404）资助项目.

Progress in C—N Bond Formation Involving C(sp²)—H Bond through Transition-Metal-Free Radical Reactions

Wu Yan^a,c, Chen Jinyang^a,c, Li Qiang^b, Wei Wenting^c

a College of Chemistry and Chemical Engineering, Yangtze Normal University, Chongqing 408000;
b School of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng, Shandong 252059;
c School of Materials Science and Chemical Engineering, Ningbo University, Ningbo, Zhejiang 315211

Received:2019-09-22 Revised:2019-10-26 Published:2020-04-02
Supported by:
Project supported by the Basic and Frontier Research Project of Chongqing (Nos. Cstc2018jcyjAX0721, Cstc2018jcyjAX0051), the Youth Talent Growth Plan Project of Yangtze Normal University (No. 2018QNRC11) and the Education Commission of Chongqing City (No. KJQN201801404).

The C-N bond is widely found in medicinal molecules, natural products and functional materials. Therefore, it has great significance to develop simple and efficient methods for the construction of C-N bond. Recently, remarkable progress has been made in construction of C-N bond involving C(sp²)-H bond through transition-metal-free radical reactions. Due to the relatively mild reaction condition and high reactivity, it provides a novel approach to construct C-N bond. In this review, the recent developments in this area are summarized on the basis of different nitrogen sources.

Key words: C—N bond, C (sp²)—H bond, transition-metal-free, radical

Cite this article

Wu Yan, Chen Jinyang, Li Qiang, Wei Wenting. Progress in C—N Bond Formation Involving C(sp²)—H Bond through Transition-Metal-Free Radical Reactions[J]. Chinese Journal of Organic Chemistry, 2020, 40(3): 589-597.

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无过渡金属体系下C (sp²)—H键的自由基反应构建C—N键研究进展

Progress in C—N Bond Formation Involving C(sp²)—H Bond through Transition-Metal-Free Radical Reactions

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无过渡金属体系下C (sp2)—H键的自由基反应构建C—N键研究进展