Chinese Journal of Organic Chemistry ›› 2004, Vol. 24 ›› Issue (10): 1274-1277. Previous Articles     Next Articles

羟基查尔酮类衍生物的合成

关丽萍, 尹秀梅, 全红梅, 全哲山*   

  1. 延边大学医学院 延吉 133000
  • 收稿日期:2003-11-03 修回日期:2004-02-02 接受日期:2004-04-20 发布日期:2022-09-20

Synthesis of Hydroxylated Chalcones and Related Derivatives

GUAN Li-Ping, YIN Xiu-Mei, QUAN Hong-Mei, QUAN Zhe-Shan*   

  1. College of Medicine, Yanbian University, Yanji 133000
  • Received:2003-11-03 Revised:2004-02-02 Accepted:2004-04-20 Published:2022-09-20
  • Contact: * E-mail: quanzheshan@yahoo.com.cn

Chalcones can be prepared through condensation of 4-hydroxyl acetophenone or 2,4-dihydroxyl acetophenone with substitued benzaldehydes in ethyl glycol solution, using the catalyst of boric acid at 110~120℃ in 6 h. The product was purified by the flash chromatography on silicagel. The structures were determinded by IR, 1H NMR and MS spectra. The method is convenient and simple, though the yield is not high.

Key words: hydroxylated chalcone, chalcone, synthesis