Chinese Journal of Organic Chemistry ›› 2023, Vol. 43 ›› Issue (9): 3210-3215.DOI: 10.6023/cjoc202302030 Previous Articles     Next Articles

水-聚乙二醇(PEG-200)中烯烃与碘代芳烃绿色可循环无负载偶联反应的研究

蒋宜欣a, 唐伯孝a,b,*(), 毛海波a, 陈雪霞a, 俞洋杰a, 全翠英a, 徐昭阳a, 石金慧a, 刘益林a,b,*()   

  1. a 怀化学院有机合成研究所 湖南怀化 418000
    b 怀化学院聚乙烯醇纤维材料制备技术湖南省工程实验室 湖南怀化 418000
  • 收稿日期:2023-02-28 修回日期:2023-05-08 发布日期:2023-05-29
  • 基金资助:
    湖南省自然科学基金(2021JJ30537); 湖南省大学生创新训练基金(S202110548054); 国家自然科学基金(21563015)

A Green, Recyclable and Carrier-Free Study for the Coupling Reaction of Alkenes with Aryl Iodides in H2O-Polyethylene Glycol (PEG-200)

Yixin Jianga, Boxiao Tanga,b(), Haibo Maoa, Xuexia Chena, Yangjie Yua, Cuiying Quana, Zhaoyang Xua, Jinhui Shia, Yilin Liua,b()   

  1. a Institute of Organic Synthesis, Huaihua University, Huaihua, Hunan 418000
    b Hunan Engineering Laboratory for Preparation Technology of Polyvinyl Alcohol (PVA) Fiber Material, Huaihua University, Huaihua, Hunan 418000
  • Received:2023-02-28 Revised:2023-05-08 Published:2023-05-29
  • Contact: E-mail: 520tangboxiao@163.com;liuyilinhn@126.com
  • Supported by:
    Natural Science Foundation of Hunan Province(2021JJ30537); University Students Innovation Training Foundation of Hunan Province(S202110548054); National Natural Science Foundation of China(21563015)

By using an environmentally friendly H2O-polyethylene glycol (PEG-200) system as the reaction medium, a new, green and recyclable protocol was developed for Pd(OAc)2-catalyzed the cross-coupling reaction of alkenes with aryl iodides. A series of coupling products can be obtained with good selectivity and yield. The Pd(OAc)2-H2O-PEG-200 system can be directly recovered and used for more than three cycles without any loss of activity, demonstrating the robustness of the carrier-free palladium catalyst system. As the reaction cost is reduced and the operation is simple, the approach is beneficial to industrial production.

Key words: carrier-free, reusability, H2O-polyethylene glycol (PEG-200), cross-coupling, green chemistry