Chinese Journal of Organic Chemistry ›› 2024, Vol. 44 ›› Issue (5): 1568-1575.DOI: 10.6023/cjoc202310018 Previous Articles Next Articles
ARTICLES
罗东红a,†, 李平a,†, 陈志才b,†, 杨佳怡a, 孙梦凡a, 陆居有a,*()
收稿日期:
2023-10-21
修回日期:
2024-01-13
发布日期:
2024-01-30
作者简介:
基金资助:
Donghong Luoa,†, Ping Lia,†, Zhicai Chenb,†, Jiayi Yanga, Mengfan Suna, Juyou Lua()
Received:
2023-10-21
Revised:
2024-01-13
Published:
2024-01-30
Contact:
*E-mail: About author:
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Donghong Luo, Ping Li, Zhicai Chen, Jiayi Yang, Mengfan Sun, Juyou Lu. Pd-Catalyzed Cross-Coupling of o-Carboranyl Pyridyl Halides: Synthesis of o-Carboranyl Biaryls, Aminopyridines and Alkynylpyridine Derivatives[J]. Chinese Journal of Organic Chemistry, 2024, 44(5): 1568-1575.
Entry | Catalyst | Base | Solvent | Yield b/% |
---|---|---|---|---|
1 | Pd(OAc)2 | CsF | THF | 35 |
2 | Pd(dba)2 | CsF | THF | 7 |
3 | Pd(PtBu3)2 | CsF | THF | 69 |
4 | Pd(PPh3)4 | CsF | THF | 13 |
5 | — | CsF | THF | 0 |
6 | Pd(PtBu3)2 | K2CO3 | THF | 27 |
7 | Pd(PtBu3)2 | K2HPO4 | THF | 29 |
8 | Pd(PtBu3)2 | Li2CO3 | THF | 32 |
9 | Pd(PtBu3)2 | Cs2CO3 | THF | 36 |
10 | Pd(PtBu3)2 | CsF | DCE | 47 |
11 | Pd(PtBu3)2 | CsF | Toluene | 42 |
12 | Pd(PtBu3)2 | CsF | 1,4-Dioxane | 44 |
13 | Pd(PtBu3)2 | CsF | CH3CN | 45 |
Entry | Catalyst | Base | Solvent | Yield b/% |
---|---|---|---|---|
1 | Pd(OAc)2 | CsF | THF | 35 |
2 | Pd(dba)2 | CsF | THF | 7 |
3 | Pd(PtBu3)2 | CsF | THF | 69 |
4 | Pd(PPh3)4 | CsF | THF | 13 |
5 | — | CsF | THF | 0 |
6 | Pd(PtBu3)2 | K2CO3 | THF | 27 |
7 | Pd(PtBu3)2 | K2HPO4 | THF | 29 |
8 | Pd(PtBu3)2 | Li2CO3 | THF | 32 |
9 | Pd(PtBu3)2 | Cs2CO3 | THF | 36 |
10 | Pd(PtBu3)2 | CsF | DCE | 47 |
11 | Pd(PtBu3)2 | CsF | Toluene | 42 |
12 | Pd(PtBu3)2 | CsF | 1,4-Dioxane | 44 |
13 | Pd(PtBu3)2 | CsF | CH3CN | 45 |
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