Aggregation-induced emission materials for tumor phototheranostics

doi:10.6023/cjoc202403059

Chinese Journal of Organic Chemistry Previous Articles Next Articles

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聚集诱导发光材料用于肿瘤光学诊疗

黄伟庚^#,a, 高翼亭^#,a,b, 孙妍^a,b, 燕鼎元^*,a, 王东^*,a, 唐本忠^*,a,c

^a深圳大学材料学院 AIE研究中心深圳 518000
^b东北师范大学化学学院吉林省高校纳米生物传感与纳米生物分析重点实验室长春 130024
^c香港中文大学（深圳）理工学院深圳分子聚集体科学与工程研究院深圳 518172

收稿日期:2024-03-31 修回日期:2024-06-19
基金资助:
国家自然科学基金(52122317, 22175120, 22307080); 深圳市自然科学基金(RCBS20221008093224016, JCYJ20220531101201003, JCYJ20190808153415062, 20220809130438001, JSGG20220606141800001, JCYJ20200109110608167); 广东省基础与应用基础研究基金(2023A1515010558)资助项目.

Aggregation-induced emission materials for tumor phototheranostics

Huang, Weigeng^#,a, Gao, Yiting^#,a,b, Sun, Yan^a,b, Yan, Dingyuan^*,a, Wang, Dong^*,a, Tang, Ben Zhong^*,a,c

^aCenter for AIE Research, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060
^bKey Laboratory of Nanobiosensing and Nanobioanalysis at Universities of Jilin Province, Department of Chemistry, Northeast Normal University, Changchun 130024
^cSchool of Science and Engineering, Shenzhen Institute of Molecular Aggregate Science and Engineering, The Chinese University of Hong Kong, Shenzhen 518172

Received:2024-03-31 Revised:2024-06-19
Contact: *E-mail: yandingyuan@szu.edu.cn; wangd@szu.edu.cn; tangbenz@cuhk.edu.cn
Supported by:
National Natural Science Foundation of China (No. 52122317, 22175120, 22307080), the Developmental Fund for Science and Technology of Shenzhen government (No. RCBS20221008093224016, JCYJ20220531101201003, JCYJ20190808153415062, 20220809130438001, JSGG20220606141800001, JCYJ20200109110608167), the Guangdong Basic and Applied Basic Research Fund (No. 2023A1515010558).

In recent years, aggregation-induced emission (AIE) materials have attracted much attention in the field of tumour treatment due to their excellent attributes of aggregation-enhanced theranostics. The AIE materials can dissipate the excited state energy through different energy relaxation pathways to generate reactive oxygen species or heat, which can be used for imaging-guided tumour phototherapy. This review systematically summarises the research progress of AIE materials for tumor phototheranostics according to the different excitation modes, specifically photogenic excitation (including the use of white light, 660 nm, 808 nm, 980 nm or 1064 nm lasers), chemical excitation, ultrasonic excitation and X-ray excitation. In addition, the advantages and limitations of each excitation energy source are briefly discussed.

Key words: aggregation-induced emission, excitation source, tumor theranostics

Cite this article

Huang, Weigeng, Gao, Yiting, Sun, Yan, Yan, Dingyuan, Wang, Dong, Tang, Ben Zhong. Aggregation-induced emission materials for tumor phototheranostics[J]. Chinese Journal of Organic Chemistry, doi: 10.6023/cjoc202403059.

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聚集诱导发光材料用于肿瘤光学诊疗

Aggregation-induced emission materials for tumor phototheranostics

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