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封面介绍The recent advances in the synthesis of bedaquilinebased antitubercular agents are reviewed by Gao and Zhang on page 3113, with emphasis on key strategies such as bimetallic cooperative catalysis. Furthermore, continuous flow technology, owing to its inherent advantages of efficiency, safety, and scalability, demonstrates considerable promise in the production of bedaquiline. Bedaquiline-based drug synthesis will become more efficient, green, and sustainable. -
封面介绍The fluorescence molecular design models based on various machine learning (ML) algorithms are reviewed by Guo, Li, Tang, and Fan on page 3203. The current research is categorized according to multiple diagnostic and therapeutic molecular characteristics, and the future development directions for molecular design using ML methods are proposed. -
封面介绍A novel method for the efficient synthesis of cyclopentenones by organic base-promoted [2＋3] annulation of arylglyoxal monohydrates with allyl phosphonium salts has been successfully developed by Zhang, Jiang, Xin, Huang and Wang on page 3420. This method displays metal-free, good chemoselectivity, mild reaction conditions, broad substrate scope, and short reaction time. -
封面介绍A dearomatization strategy using dicetolic acid (6) as the starting material to synthesize the core intermediate (10R,13S,14S)-10,13-dimethyl-7,10,11,12,13,14,15,16- octahydro-3H-cyclopenta[a]phenanthrene-3,17(6H)-dione (20) for the formal synthesis of dydrogesterone is presented by Yao, Wang, Yuan, Zeng, Jiang, Zou, Ren, Zhang, and Zeng on page 3478, achieving a total yield of 21% over nine steps. This approach features an environmentally friendly carbonyl protection strategy and efficient Heck coupling.
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本期栏目
目录
综述与进展
有机化学
2025, 45 (9), pp 3045-3074
DOI: 10.6023/cjoc202506002
有机化学
2025, 45 (9), pp 3075-3097
DOI: 10.6023/cjoc20205031
有机化学
2025, 45 (9), pp 3098-3112
DOI: 10.6023/cjoc202505029
有机化学
2025, 45 (9), pp 3113-3127
DOI: 10.6023/cjoc202505017
有机化学
2025, 45 (9), pp 3128-3147
DOI: 10.6023/cjoc202505023
有机化学
2025, 45 (9), pp 3148-3162
DOI: 10.6023/cjoc202507032
有机化学
2025, 45 (9), pp 3163-3174
DOI: 10.6023/cjoc202506025
有机化学
2025, 45 (9), pp 3175-3185
DOI: 10.6023/cjoc202506006
有机化学
2025, 45 (9), pp 3186-3202
DOI: 10.6023/cjoc202504011
有机化学
2025, 45 (9), pp 3203-3212
DOI: 10.6023/cjoc20205022
有机化学
2025, 45 (9), pp 3213-3243
DOI: 10.6023/cjoc202503010
有机化学
2025, 45 (9), pp 3244-3254
DOI: 10.6023/cjoc202502021
有机化学
2025, 45 (9), pp 3255-3288
DOI: 10.6023/cjoc202502036
有机化学
2025, 45 (9), pp 3289-3300
DOI: 10.6023/cjoc202502022
有机化学
2025, 45 (9), pp 3301-3313
DOI: 10.6023/cjoc202503015
有机化学
2025, 45 (9), pp 3314-3325
DOI: 10.6023/cjoc202502024
研究论文
有机化学
2025, 45 (9), pp 3326-3334
DOI: 10.6023/cjoc202505032
有机化学
2025, 45 (9), pp 3335-3342
DOI: 10.6023/cjoc202504010
有机化学
2025, 45 (9), pp 3343-3350
DOI: 10.6023/cjoc202504018
有机化学
2025, 45 (9), pp 3351-3360
DOI: 10.6023/cjoc202506005
有机化学
2025, 45 (9), pp 3361-3369
DOI: 10.6023/cjoc202503008
有机化学
2025, 45 (9), pp 3370-3377
DOI: 10.6023/cjoc202501018
有机化学
2025, 45 (9), pp 3378-3391
DOI: 10.6023/cjoc202503011
有机化学
2025, 45 (9), pp 3390-3400
DOI: 10.6023/cjoc202503019
有机化学
2025, 45 (9), pp 3401-3411
DOI: 10.6023/cjoc202505016
有机化学
2025, 45 (9), pp 3412-3419
DOI: 10.6023/cjoc202502035
有机化学
2025, 45 (9), pp 3420-3428
DOI: 10.6023/cjoc202502010
有机化学
2025, 45 (9), pp 3429-3440
DOI: 10.6023/cjoc202502008
有机化学
2025, 45 (9), pp 3441-3449
DOI: 10.6023/cjoc202501013
有机化学
2025, 45 (9), pp 3450-3457
DOI: 10.6023/cjoc202503012
有机化学
2025, 45 (9), pp 3458-3468
DOI: 10.6023/cjoc202502019
有机化学
2025, 45 (9), pp 3469-3477
DOI: 10.6023/cjoc202502038
有机化学
2025, 45 (9), pp 3478-3485
DOI: 10.6023/cjoc202502033
研究简报
有机化学
2025, 45 (9), pp 3486-3489
DOI: 10.6023/cjoc202502012
亮点述评
有机化学
2025, 45 (9), pp 3490-3491
DOI: 10.6023/cjoc202500020
有机化学
2025, 45 (9), pp 3492-3494
DOI: 10.6023/cjoc202500021
