有机化学 ›› 2012, Vol. 32 ›› Issue (10): 1864-1871.DOI: 10.6023/cjoc1110262 上一篇    下一篇

综述与进展

叔丁醇钾促进的形成碳—碳及碳—杂键的偶联反应的研究进展

王良贵a, 严国兵a, 张鑫燕b   

  1. a 丽水学院化学系 丽水 323000;
    b 丽水职业技术学院 丽水 323000
  • 收稿日期:2011-10-26 修回日期:2012-04-16 发布日期:2012-05-18
  • 通讯作者: 严国兵 E-mail:gbyan@lsu.edu
  • 基金资助:

    浙江省自然科学基金(No. Y4110324)资助项目.

Recent Progress in the Research of the t-BuOK-Mediated Coupling Reactions to Form Carbon-Carbon and Carbon-Heteroatom Bonds

Wang Liangguia, Yan Guobinga, Zhang Xinyanb   

  1. a Department of Chemistry, Lishui University, Lishui 323000;
    b Lishui Vocational & Technical College, Lishui 323000
  • Received:2011-10-26 Revised:2012-04-16 Published:2012-05-18
  • Supported by:

    Project supported by the Natural Science Foundation of Zhejiang Province (No. Y4110324).

叔丁醇钾由于其碱性强而亲核性相对较弱在有机合成中得到广泛应用. 综述了近年来叔丁醇钾促进的交叉偶联反应的研究进展, 主要包括碳-碳、碳-氮及碳-氧键的形成及其反应机理的探讨.

关键词: 叔丁醇钾, 偶联反应, 反应机理, 进展

Potassium tert-butoxide has wide application as a strong base and weak nucleophilie in organic chemistry. In this paper, the newest development of the t-BuOK-mediated coupling reactions is reviewed. The main focuses are the formation of carbon-carbon, carbon-nitrogen and carbon-oxygen bonds. The formation mechanisms of these bonds are discussed in details.

Key words: potassium-tert-butoxide, coupling reaction, reaction mechanism, progress