有机化学 ›› 2013, Vol. 33 ›› Issue (12): 2602-2606.DOI: 10.6023/cjoc201307030 上一篇    下一篇

研究简报

微波辐照下烯烃和重氮化合物无催化剂的环丙烷化反应

蔡少君a, 肖龙强b, 廖立琼b, 刘立建b   

  1. a 江汉大学光电化学材料与器件省部共建教育部重点实验室 武汉 430056;
    b 武汉大学化学与分子科学学院 武汉 430072
  • 收稿日期:2013-07-19 修回日期:2013-08-19 出版日期:2013-12-25 发布日期:2013-08-29
  • 通讯作者: 刘立建 E-mail:liulj@whu.edu.cn
  • 基金资助:

    国家自然科学基金(Nos. 21074097,21274112)、光电化学材料与器件教育部重点实验室开放项目基金(No. JDGD-2012-07)资助项目.

Catalyst-Free Cyclopropanation of Alkenes with Diazocompounds under Microwave Irradiation

Cai Shaojuna, Xiao Longqiangb, Liao Liqiongb, Liu Lijianb   

  1. a Key Laboratory of Optoelectronic Chemical Materials and Devices of Ministry of Education, Jianghan University, Wuhan 430056;
    b College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072
  • Received:2013-07-19 Revised:2013-08-19 Online:2013-12-25 Published:2013-08-29
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos. 21074097, 21274112), and the Found of Key Laboratory of Optoelectronic Chemical Materials and Devices of Ministry of Educatio (No. JDGD-2012-07).

在微波辐照下,重氮化合物和烯烃通过环丙烷化反应合成了环丙烷化合物. 和传统需要金属催化剂的合成方法相比,该方法具有简便、对环境危害小等特点. 同时,动力学研究结果表明微波辐照下的环丙烷化反应是二级反应.

关键词: 重氮化合物, 环丙烷化, 微波, 动力学研究, 绿色化学

Cyclopropane derivatives were prepared by the reaction of diazocompounds and alkene without catalyst under microwave irradiation, which demonstrated that it is an efficient method in organic chemistry. Compared with traditional metal catalyzed cyclopropane, this method is convenient and less harmful to environment. A second-order process was involved in the cyclopropanation as shown by the kinetic study.

Key words: cyclopropanation, diazocompound, microwave, kinetic study, green chemistry