Chin. J. Org. Chem. ›› 2016, Vol. 36 ›› Issue (5): 1143-1147.DOI: 10.6023/cjoc201509046 Previous Articles     Next Articles

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钯催化合成氧化芪三酚的研究

李志伟a, 康绍英b, 陈琳a, 王宇a, 李江胜a   

  1. a. 电力与交通材料保护湖南省重点实验室 长沙理工大学化学与生物工程学院 长沙 410114;
    b. 湖南省食品质量监督检验研究院 长沙 410111
  • 收稿日期:2015-09-30 修回日期:2015-12-03 出版日期:2016-05-25 发布日期:2016-01-04
  • 通讯作者: 李志伟, 李江胜 E-mail:lizwhn@126.com;jslichem@gmail.com
  • 基金资助:

    湖南省自然科学基金(No.2015JJ3012)、湖南省教育厅(No.14C0050)和电力与交通材料保护湖南省重点实验室(No.2016CL01)资助项目.

Study on the Synthesis of Oxyresveratrol Catalyzed by Palladium

Li Zhiweia, Kang Shaoyingb, Chen Lina, Wang Yuaa, Li Jiangshenga   

  1. a. Hunan Provincial Key Laboratory of Materials Protection for Electric Power and Transportation, School of Chemistry and Biological Engineering, Changsha University of Science and Technology, Changsha 410114;
    b. Hunan Institute of Food Quality Supervision Inspection and Research, Changsha 410111
  • Received:2015-09-30 Revised:2015-12-03 Online:2016-05-25 Published:2016-01-04
  • Supported by:

    Project supported by the Natural Science Foundation of Hunan Province (No. 2015JJ3012), the Scientific Research Fund of Hunan Provincial Education Department (No. 14C0050) and Hunan Provincial Key Laboratory of Materials Protection for Electric Power and Transportation (2016CL01).

A convenient method for the synthesis of oxyresveratrol catalyzed by palladium is described. 2,4-Dihydroxyiodo-benzene underwent Heck reaction with acrylic acid, then decarboxylation, and further underwent Heck reaction with 3,5-dihydroxyiodobenzene, furnishing oxyresveratrol in a high yield. The title compound was characterized by MS and NMR. This synthetic method has several advantages such as less step processes, high yield, simple operations, and promises to be applied in industrial production.

Key words: decarboxylation, oxyresveratrol, palladium catalysis, heck reaction