Chin. J. Org. Chem. ›› 2017, Vol. 37 ›› Issue (12): 3163-3169.DOI: 10.6023/cjoc201707003 Previous Articles     Next Articles



朱晓宇, 赵亚楠, 兰丽艳, 李文泽   

  1. 沈阳化工大学应用化学学院 沈阳 110142
  • 收稿日期:2017-07-04 修回日期:2017-08-23 发布日期:2017-09-15
  • 通讯作者: 李文泽
  • 基金资助:


Enantioselective Organocatalytic Intramolecular Friedel-Crafts Alkylations of Pyrrole-Type Aryloxy-and Arylamino-tethered Enals: Access to a New Class of Pyrrole-Fused Heterocycles

Zhu Xiaoyu, Zhao Yanan, Lan Liyan, Li Wenze   

  1. College of Applied Chemistry, Shenyang University of Chemical Technology, Shenyang 110142
  • Received:2017-07-04 Revised:2017-08-23 Published:2017-09-15
  • Contact: 10.6023/cjoc201707003
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21502118).

The catalytic asymmetric one-pot tandem intermolecular olefin cross-metathesis/intramolecular Friedel-Crafts alkylation with aryloxy-and arylamino-tethered enals as building blocks was developed, which offers a direct and convenient access to a novel type of pyrrole-fused heterocyclic compounds in good yields with synthetically useful enantioselectivities.

Key words: pyrrole-fused heterocycles, olefin cross-metathesis, Friedel-Crafts alkylation, asymmetric synthesis, one pot