Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (1): 61-68.DOI: 10.6023/cjoc201905022 Previous Articles     Next Articles

钯催化二芳基膦氢对萘醌单酮的不对称1,4-加成反应

孙贵救a, 肖繁花a, 段伟良b   

  1. a 上海应用技术大学化学与环境工程学院 上海 200237;
    b 扬州大学化学化工学院 江苏扬州 225002
  • 收稿日期:2019-05-11 修回日期:2019-08-29 出版日期:2020-01-25 发布日期:2019-09-12
  • 通讯作者: 肖繁花, 段伟良 E-mail:fhxiao@sit.edu.cn;duanwl@yzu.edu.cn
  • 基金资助:
    国家自然科学基金(Nos.21472218,21672183)资助项目.

Palladium-Catalyzed Asymmetric 1,4-Addition of Diarylphosphines to Quinone Monoketals

Sun Guijiua, Xiao Fanhuaa, Duan Weiliangb   

  1. a School of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai 201418;
    b College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou 225002
  • Received:2019-05-11 Revised:2019-08-29 Online:2020-01-25 Published:2019-09-12
  • Supported by:
    Project supported by the National Natural Science Foundation of China (Nos. 21472218, 21672183).

An asymmetric 1,4-addition reaction of diarylphosphines with quinone monoketals was studied. Pincer Pd complex was used as catalyst to generate a series of chiral phosphorus compounds with moderate to good enantioselectivities in high yields.

Key words: palladium catalysis, diarylphosphine, asymmetric addition