Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (9): 2725-2741.DOI: 10.6023/cjoc202003054 Previous Articles     Next Articles


王溯, 张友璐, 巴妍妍, 张京玉, 孙德梅   

  1. 河南中医药大学药学院 郑州 450046
  • 收稿日期:2020-03-23 修回日期:2020-05-10 发布日期:2020-05-28
  • 通讯作者: 孙德梅
  • 基金资助:

Study and Applications of Stereoselective Olefin Metathesis Reactions

Wang Su, Zhang Youlu, Ba Yanyan, Zhang Jingyu, Sun Demei   

  1. College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046
  • Received:2020-03-23 Revised:2020-05-10 Published:2020-05-28
  • Supported by:
    Project supported by the Science & Technology Innovation Talents of Henan University of Chinese Medicine (No. 2014XCXRC01) and the Henan University of Chinese Medicine, Provincial Scientific Research Business (No. 2014KYYWF-ZZCX3-05).

Olefin metathesis has been one of the most important methods to construct carbon-carbon double bonds, which has been catalyzed by ruthenium carbene. Investigations in olefin metathesis have focused on stereoselective transformations in recent years. The research progress on the applications of stereoselective olefin metathesis reactions catalyzed by ruthenium carbene complexes is reviewed. The advancements in stereoselectivity of olefin metathesis are described in detail, and the categories and improvement of ruthenium catalysts are also introduced over the past decade. Finally, the future development for olefin metathesis is further evaluated as well.

Key words: olefin metathesis, ruthenium, catalyst, stereoselective