Chinese Journal of Organic Chemistry ›› 2022, Vol. 42 ›› Issue (5): 1431-1437.DOI: 10.6023/cjoc202112028 Previous Articles     Next Articles


烯烃自由基胺硒化: β-氨基硒醚的简易合成

殷一樊a, 李晨b, 孙凯c,*(), 刘颖杰b, 王薪c,*()   

  1. a 新墨西哥州立大学化学与生物化学系 新墨西哥州 88011
    b 哈尔滨商业大学药学院 哈尔滨 150076
    c 烟台大学化学化工学院 山东烟台 264005
  • 收稿日期:2021-12-21 修回日期:2022-01-28 发布日期:2022-02-10
  • 通讯作者: 孙凯, 王薪
  • 基金资助:

Radical Aminoselenation of Styrenes: Facile Access to β-Amido-selenides

Yifan Yina, Chen Lib, Kai Sunc(), Yingjie Liub, Xin Wangc()   

  1. a Department of Chemistry & Biochemistry, New Mexico State University, New Mexico, 88011 USA
    b School of Pharmacy, Harbin University of Commerce, Harbin 150076
    c College of Chemistry and Chemical Engineering, Yantai University, Yantai, Shandong 264005
  • Received:2021-12-21 Revised:2022-01-28 Published:2022-02-10
  • Contact: Kai Sun, Xin Wang
  • Supported by:
    National Natural Science Foundation of China(21801007)

An efficient protocol for the intermolecular amidoselenation of alkenes with diphenyl diselenides and alkyl amines has been developed, affording a series of β-amido-selenides in high yields under copper salt and (diacetoxyiodo)benzene (PIDA) conditions. The preliminary experimental results supported the involvement of active selenide radical species, and a radical pathway was therefore proposed for the reaction.

Key words: amidoselenation, β-amido-selenide, active selenide, radical