有机化学 ›› 2018, Vol. 38 ›› Issue (7): 1586-1595.DOI: 10.6023/cjoc201802021 上一篇    下一篇

所属专题: 元素有机化学合辑2018-2019

综述与进展

线性二芳基碘盐在杂原子芳基化中的应用研究进展

马姣丽, 陈立成, 袁中文, 程辉成   

  1. 广东石油化工学院化学工程学院 茂名 525000
  • 收稿日期:2018-02-22 修回日期:2018-04-02 发布日期:2018-04-13
  • 通讯作者: 程辉成 E-mail:awchengcheng@163.com
  • 基金资助:

    茂名市科技计划项目(No.917313)、广东石油化工学院人才引进(No.517152)、广东石油化工学院青年创新人才培育(No.517136)、广东大学生攀登计划(No.pdjh2017b0343)及广东石油化工学院大学生创新创业培育计划(No.2017pyA006)资助项目.

Recent Advance of Acyclic Diaryliodonium Salts in Arylation of Heteroatom

Ma Jiaoli, Chen Licheng, Yuan Zhongwen, Cheng Huicheng   

  1. College of Chemcal Engineering, Guangdong University of Petrochemical Technology, Maoming 525000
  • Received:2018-02-22 Revised:2018-04-02 Published:2018-04-13
  • Contact: 10.6023/cjoc201802021 E-mail:awchengcheng@163.com
  • Supported by:

    Project supported by the Maoming City Technology Bureau (No. 917313), the Guangdong University of Petrochemical Technology (Nos. 517152, 517136, 2017pyA006).

有机高价碘盐化合物作为一种低毒性、对环境友好、高反应活性的试剂,受到了广泛的关注.线性二芳基碘盐是一类重要的高价碘试剂,常在有机合成中作为芳基阳离子试剂进行芳基化反应,在有机合成领域具有广泛的应用.在温和的条件下,线性二芳基碘盐与亲核试剂反应成为高效构建杂原子芳基化的有效手段之一.按照成键类型分类讨论线性二芳基碘盐在杂原子(包括氧、氮、硫、磷等)芳基化反应中的应用,并就该领域的的发展前景进行展望.

关键词: 线性二芳基碘盐, 杂原子, 芳基化

As a kind of low toxicity, environmentally friendly, high reaction activity reagent, hypervalent iodine compounds have received the widespread attention. Acyclic diaryl iodonium salt as aryl cationic reagent, has an important application in organic synthesis. Under mild conditions, diaryl iodonium salt can react with nucleophilic reagent, which has been one of the effective means of the arylation of heteroatom. According to the classification of chemical bond formation, the application of the acyclic diaryl iodonium salt in the arylation of heteroatom (including oxygen, nitrogen, sulfur, phosphorus, etc.) is discussed and the development direction in the field is prospected.

Key words: acyclic diaryl iodonium salt, heteroatom, arylation