有机化学 ›› 2021, Vol. 41 ›› Issue (4): 1543-1550.DOI: 10.6023/cjoc202012009 上一篇    下一篇

研究论文

新型手性三联吡啶钌(II)配合物催化酮到醇的氢转移反应

王小蝶1, 刘春玉1, 苗玲玲1, 薛冰洁1, 朱新举1, 宋冰1,*(), 郝新奇1,*(), 刘国际1   

  1. 1 郑州大学化学学院 生命科学学院 郑州 450001
  • 收稿日期:2020-12-04 修回日期:2020-12-07 发布日期:2020-12-10
  • 通讯作者: 宋冰, 郝新奇
  • 基金资助:
    国家自然科学基金(21672192); 国家自然科学基金(21803059); 国家自然科学基金(U1904212)

Transfer Hydrogenation of Ketones into Alcohols Catalyzed by a Novel Chiral Terpyridine Ruthenium(II) Complex

Xiaodie Wang1, Chunyu Liu1, Lingling Miao1, Bingjie Xue1, Xinju Zhu1, Bing Song1,*(), Xinqi Hao1,*(), Guoji Liu1   

  1. 1 School of Life Sciences, College of Chemistry, Zhengzhou University, Zhengzhou 450001
  • Received:2020-12-04 Revised:2020-12-07 Published:2020-12-10
  • Contact: Bing Song, Xinqi Hao
  • About author:
    * Corresponding authors. E-mail: ;
  • Supported by:
    National Natural Science Foundation of China(21672192); National Natural Science Foundation of China(21803059); National Natural Science Foundation of China(U1904212)

合成了一个含有手性对称三联吡啶配体的新型阳离子钌配合物, 并通过核磁共振、高分辨质谱和X射线单晶衍射确证了其结构. 该配合物在酮的氢转移中表现出较好的催化活性. 在最优条件下, 各种酮都可以在相对温和的条件下顺利通过氢化反应高效地生成相应的醇, 最高收率为99%.

关键词: 钌(II)配合物, 手性三联吡啶, 氢转移

A novel cationic ruthenium(II) complex bearing a chiral symmetrical pineno-fused terpyridine ligand was synthesized and structurally characterized by NMR, HRMS, and X-ray crystallographic determinations. This complex exhibited good catalytic activity in the transfer hydrogenation of ketones. Under optimized conditions, a wide range of ketones underwent hydrogenation smoothly to furnish corresponding alcohols in excellent yields (up to 99%) under relative mild reaction conditions.

Key words: Ru(II) complexe, chiral terpyridine, transfer hydrogenation