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有机化学
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有机化学 ›› 1992, Vol. 12 ›› Issue (2): 168-172. 上一篇    下一篇

研究论文

2-取代-环戊烯酮及其衍生物的简易合成

孙诗澄;邱发洋;刘铸晋   

  1. 中国科学院上海有机化学研究所
  • 发布日期:1992-04-25

A Facile synthesis of 2-substituted cyclopentenone and their derivatives

SUN SHICHENG;QIU FAYANG;LIU ZHUJIN   

  • Published:1992-04-25

被引次数

1

本文报道以2-氯环戊酮的加成重排反应合成2-取代环戊酮。如再引入硫硫双键,则可合成2-取代环戊烯酮。取代环戊酮和取代环戊烯酮是合成药物和合成香料的重要中间体。

关键词: 红外分光光度法, 环戊酮 P, 二氢茉莉酮酸甲酯, 质谱法, 有机硅化合物, 加成反应, 核磁共振谱法, 重排反应, 环戊酮 P, 环戊烯酮 P

Reaction of 2-chlorocyclopentanone with RMgBr (R = Et, pentyl, Ph) gave 61-75% cyclopentanone I, bromination and dehydrobromination of which gave cyclopentenones II. II (R = pentyl, Ph) were converted to cyclopentanones III in 2 steps.

Key words: MASS SPECTROGRAPHY, INFRARED SPECTROPHOTOMETRY, METHYLDIHYDROJASMONATE, NMR SPECTROMETRY, ADDITION REACTION, ORGANO SILICON COMPOUNDS, CYCLOPENTENONE P, REARRANGEMENT REACTION, CYCLOPENTANONE P, CYCLOPENTANONE P

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