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有机化学
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有机化学 ›› 2011, Vol. 31 ›› Issue (03): 275-285.    下一篇

综述与进展

环糊精衍生物的点击化学合成法的研究进展

安伟, 张华承, 孙涛, 李祥军, 郝爱友   

  1. (山东大学化学与化工学院 济南250100)
  • 收稿日期:2010-01-20 修回日期:2010-06-09 发布日期:2010-09-05
  • 通讯作者: 郝爱友 E-mail:haoay@sdu.edu.cn

Progress on Cyclodextrin Derivatives Synthesized via “Click” Chem-istry

AN Wei, ZHANG Hua-Cheng, SUN Tao, LI Xiang-Jun, HAO Ai-You   

  1. (School of Chemistry & Chemical Engineering, Shandong University, Jinan 250100)
  • Received:2010-01-20 Revised:2010-06-09 Published:2010-09-05

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1853

被引次数

22 | 5

点击化学(“click” chemistry)具有反应条件温和、选择性高、产率高、纯化步骤简单等优点, 现已成为当前的一大研究热点. 环糊精具有“内疏水、外亲水”的锥筒状空腔结构, 是超分子化学的重要主体之一, 合成功能各异的环糊精衍生物引起了人们的广泛关注. 综述了点击反应合成环糊精衍生物的最新研究进展及其应用, 并对其发展前景做了展望.

关键词: 点击化学, 环糊精, 有机合成, 超分子化学, 应用

“Click” chemistry has become a hot issue in present because of their mild reaction conditions, high selectivity, high yields and simple purification steps. Cyclodextrin and their derivatives (CDs) having skirt-shaped cyclic oligosaccharides with a hydrophobic inner cavity and a hydrophilic outside surface are important hosts of supramolecular chemistry. Synthesizing CDs with various properties has gained much attention. In this paper, CDs synthesized via “click” reaction and their applications are reviewed. Based on these reviews, the prospect is discussed.

Key words: “click&rdquo, chemistry, cyclodextrin, organic synthesis, supramolecular chemistry, application