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有机化学
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有机化学 ›› 2010, Vol. 30 ›› Issue (10): 1455-1467. 上一篇    下一篇

综述与进展

抗耐药性病原菌感染以及具有多药耐药逆转活性的天然产物研究进展

杨贺1，马晨*,1,2   

  1. (1山东大学化学与化工学院 济南250100)
    (2北京大学天然药物及仿生药物国家重点实验室 北京100191)
  • 收稿日期:2009-08-27 修回日期:2009-12-22 发布日期:2010-04-20
  • 通讯作者: 马晨 E-mail:chenma@sdu.edu.cn
  • 基金资助:

    国家自然科学基金;国家级.国家自然科学基金

Advances in Research on Natural Products with Anti-drug Resistance or Multidrug Resistance Reversal Activities

Yang He1 Ma Chen*,1,2   

  1. (1 School of Chemistry and Chemical Engineering, Shandong University, Jinan 25010)
    (2 State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191)
  • Received:2009-08-27 Revised:2009-12-22 Published:2010-04-20
  • Contact: MA Chen E-mail:chenma@sdu.edu.cn

PDF

1630

被引次数

7

综述了近年来抗耐药性病原菌感染和具有多药耐药逆转活性的天然产物的研究进展, 重点介绍了这类天然产物的结构特征、生理活性和部分化合物的全合成研究.

关键词: 抗耐药性, 多药耐药逆转活性, 天然产物, 全合成

The recent progress in the studies on natural products processing anti-drug resistance or multidrug resistance reversal activities is reviewed. The structural feature and biological activities of these natural products are described in detail and the total synthesis of some compounds is also provided.

Key words: anti-drug resistance, multidrug resistance reversal activity, natural product, total synthesis