有机化学 ›› 2013, Vol. 33 ›› Issue (03): 611-614.DOI: 10.6023/cjoc201211002 上一篇    下一篇

研究论文

双阳离子型室温离子液体中Suzuki偶联反应研究

张传越, 石若冰, 陈才元, 金传明   

  1. 湖北师范学院污染物分析与资源化技术湖北省重点实验室 黄石 435002
  • 收稿日期:2012-11-01 修回日期:2012-11-22 发布日期:2012-11-26
  • 通讯作者: 金传明 E-mail:jincm1999@yahoo.com
  • 基金资助:

    国家自然科学基金(No. 21171053)和湖北省教育厅基金(No. Z20102501)资助项目.

Suzuki Cross-Coupling Reactions in Dicationic Room Temperature Ionic Liquid

Zhang Chuanyue, Shi Ruobing, Chen Caiyuan, Jin Chuanming   

  1. Hubei Normal University, Hubei Province Key Laboratory of Pollutant Analysis and Reuse Technology, Huangshi 435002
  • Received:2012-11-01 Revised:2012-11-22 Published:2012-11-26
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21171053) and the Science Foundation of Hubei Provincial Department of Education (No. Z20102501).

合成了具有钳子型的双咪唑阳离子核的室温离子液体2, 它的相转变温度为-51 ℃, 热力学分解温度为412 ℃, 利用该离子液体作反应溶剂研究了不同钯催化剂PdCl2, Pd(OAc)2, Pd-NHC配合物3存在下的Suzuki偶联反应. 结果表明: 在NaOAc作碱, 0.5 mol%的Pd-NHC配合物3存在下溴代苯衍生物与苯硼酸反应具有较高的活性, 产率可以达到85%以上, Pd-NHC配合物3催化剂能更好地负载在钳子型双阳离子核室温离子液体2中, 该反应体系能重复循环使用多次, 且分离简单、重现性强、环境友好.

关键词: 室温离子液体, Suzuki偶联反应, N-杂卡宾配合物,

Room temperature ionic liquid (RTIL) 2 with pincer bisimidazole cationic nuclei was prepared. Its phase transition and thermal decomposition temperature are -51 and 412 ℃, respectively. Suzuki reactions have been studied when different catalyst PdCl2, Pd(OAc)2, Pd-N-heterocyclic carbene complex 3 were used in RTIL 2. The results indicate that aryl bromide can react with phenylboronic acid in the yield of over 85% in the presence of NaOAc and 0.5 mol% Pd-NHC 3, and the loading capability of Pd-NHC 3 in RTIL 2 is best. This high efficient catalytic system is environmentally benign, recoverable and easily separated with products.

Key words: room temperature ionic liquids, Suzuki cross-coupling reactions, N-heterocyclic carbene complex, palladium