有机化学 ›› 2013, Vol. 33 ›› Issue (06): 1167-1185.DOI: 10.6023/cjoc201303047 上一篇    下一篇

综述与进展

具有反式六氢茚满结构的萜类化合物的合成研究进展

乐贵洲a,b, 黄轩a, 刘波a,c   

  1. a 四川大学化学学院 绿色化学与技术教育部重点实验室 成都 610064;
    b 四川农业大学生命科学与理学院 雅安 625014;
    c 中国科学院上海有机化学研究所 中国科学院天然产物合成化学重点实验室 上海 200032
  • 收稿日期:2013-03-28 修回日期:2013-05-23 发布日期:2013-05-24
  • 通讯作者: 刘波 E-mail:chembliu@scu.edu.cn
  • 基金资助:

    国家自然科学基金(Nos.20872098, 21021001, 21172154);国家重点基础研究发展规划(973计划, No.2010CB833200)资助项目.

Progress in the Total Syntheses of trans-Hydrindane-Containing Terpenoids

Yue Guizhoua,b, Huang Xuana, Liu Boa,c   

  1. a Key Laboratory of Green Chemistry & Technology of Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064;
    b School of Life and Science, Sichuan Agricultural University, Ya'an 625014;
    c Key Laboratory of Synthetic Chemistry of Natural Substances, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032
  • Received:2013-03-28 Revised:2013-05-23 Published:2013-05-24
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos.20872098, 21021001, 21172154), the National Basic Research Program of China (973 Program, No.2010CB833200).

萜类化合物是天然产物化学研究的热点领域之一, 是发现和寻找药物先导化合物的重要来源.具有反式六氢茚满结构的萜类化合物由于其结构的复杂性及良好的生物活性引起了有机合成化学家的广泛关注, 重点介绍了构建萜类化合物中反式六氢茚满结构单元的合成方法及策略.

关键词: 萜类, 反式六氢茚满, 全合成

Terpenoids are one of hotspots in the field of chemical study of natural products and important sources of discovering potential drug leads.trans-Hydrindane-containing terpenoids attracted many organic chemists' attention because of their complex structures and versatile bioactivities.This review focuses on the synthetic methodologies and strategies toward the trans-hydrindane motif in terpenoids.

Key words: terpenoids, trans-hydrindane, total synthesis