有机化学 ›› 2016, Vol. 36 ›› Issue (6): 1151-1162.DOI: 10.6023/cjoc201603042 上一篇    下一篇

综述与进展

氧气存在下自由基对不饱和键的双官能化反应 2017-2018 Awarded

许健a, 宋秋玲a,b   

  1. a 华侨大学化工学院新一代物质转化研究所厦门 361021;
    b 中国科学院化学研究所分子科学国家重点实验室北京 100190
  • 收稿日期:2016-01-02 修回日期:2016-01-20 发布日期:2016-04-29
  • 通讯作者: 宋秋玲 E-mail:qsong@hqu.edu.cn
  • 基金资助:

    国家自然科学基金(No.21202049)、国家青年千人计划、福建省百人计划、华侨大学科技创新及领军人才计划(No.Z14X0047)资助项目.

Radical Promoted Difunctionalization of Unsaturated Carbon-Carbon Bonds in the Presence of Dioxygen

Xu Jiana, Song Qiulinga,b   

  1. aInstitute of Next Generation Matter Transformation, College of Chemical Engineering, Huaqiao University, Xiamen 361021;
    b National Laboratory for Molecular Sciences, Institute of Chemistry, Chinese Academy of Siences, Beijing 100190
  • Received:2016-01-02 Revised:2016-01-20 Published:2016-04-29
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21202049), the Recruitment Program of Global Experts (1000 Talents Plan), the Fujian Hundred Talents Plan and the Program of Innovative Research Team of Huaqiao University (No. Z14X0047).

碳碳不饱和键的双官能团化反应是有机合成的一种重要策略. 近年来, 利用自由基与氧气对不饱和键的双官能团化反应引起化学家们的广泛关注, 并取得了诸多的研究进展. 该类反应以氧气为反应试剂, 提供了一种绿色、高原子经济性的合成醇或者酮的方法. 按自由基类型不同, 对近年来在氧气参与下不饱和键的双官能团化反应的研究进展进行综述.

关键词: 自由基, 双官能团化, 烯烃, 炔烃

The difunctionalization of unsaturated carbon-carbon bonds is a powerful strategy for the synthesis of various organic compounds. Recently, the remarkable progress has been made in difunctionalization of unsaturated carbon-carbon bonds with dioxygen and radicals. The present protocol, which utilizes dioxygen as oxygen source, provides a green and atom economy approach to alcohols or ketones. This review will summarize the recent development in this area on the basis of different types of radicals.

Key words: radical, difunctionalization, olefin, alkyne