SIOC English
有机化学
高级检索

有机化学 ›› 2004, Vol. 24 ›› Issue (9): 1038-1041. 上一篇    下一篇

研究论文

手性铜催化剂催化的α-重氮酮的环化反应

程青芳*,a, 许兴友a, 高健b, 尤田耙c   

  1. a淮海工学院化工系 连云港 222005;
    b南京理工大学材料化学实验室 南京 210094;
    c中国科学技术大学化学系 合肥 230026
  • 收稿日期:2003-02-21 修回日期:2003-09-15 接受日期:2004-03-10 发布日期:2022-09-20

Asymmetric Cyclization of α-Diazoketones Catalyzed by Chiral Copper Catalyst

CHENG Qing-Fang*,a, XU Xing-Youa, GAO Jianb, YOU Tian-Pac   

  1. aDepartment of Chemical Technology, Huaihai Institute of Technology, Lianyungang 222005;
    bMeterials Chemistry Laboratory, Nanjing University of Sciene and Technology, Nanjing 210094;
    cDepartment of Chemistry, University of Science and Technology of China,Hefei 230026
  • Received:2003-02-21 Revised:2003-09-15 Accepted:2004-03-10 Published:2022-09-20
  • Contact: * E-mail: cheng-qingfang@yahoo.com.cn

PDF

164

首次用手性(β-二酮)-铜配合物Cu(dcm)2来催化α-重氮酮的分子内环化反应,获得很高的化学产率和中等程度的光学收率,并考察了底物结构对反应的化学产率和光学收率的影响.

关键词: 手性催化剂, α-重氮酮, 环化反应

A chiral β-diketone Cu(II) catalyst Cu(dcm)2 was synthesized and used for the asymmetric cyclization of α-diazoketones, and high chemical yields and good enantioselectivity of products were achieved. The effect of the structure of substrate on the enantioselectivity was studied.

Key words: chiral catalyst, α-diazoketone, cyclization