Chin. J. Org. Chem. ›› 2012, Vol. 32 ›› Issue (12): 2390-2393.DOI: 10.6023/cjoc201207017 Previous Articles     Next Articles

Notes

全氟辛基磺酸茂锆催化吲哚与羰基化合物反应

易卫国a,b, 贾振永b, 李宁波b, 邱仁华b, 陈锦杨b, 许新华b   

  1. a 湖南化工职业技术学院 株洲 412004;
    b 湖南大学化学化工学院 长沙 410082
  • 收稿日期:2012-07-12 修回日期:2012-08-06 发布日期:2012-08-10
  • 通讯作者: 许新华 E-mail:xhx1581@yahoo.com.cn
  • 基金资助:
    国家自然科学基金(Nos. 21172061, 21273068)资助项目.

Zirconocene Bis(perfluorooctanesulfonate)s-Catalyzed the Reaction of Indoles and Carbonyl Compounds

Yi Weiguoa,b, Jia Zhenyongb, Li Ningbob, Qiu Renhuab, Chen Jinyangb, Xu Xinhuab   

  1. a Hunan Chemical Industry Vocation Technology Institute, Zhuzhou 412004;
    b College of Chemistry Chemical Engineering, Hunan University, Changsha 410082
  • Received:2012-07-12 Revised:2012-08-06 Published:2012-08-10
  • Supported by:
    Project supported by the National Natural Science Foundation of China (Nos. 21172061, 21273068).

In the presence of 1.0 mol% zirconocene bis(perfluorooctanesulfonate)s, indoles reacted with aldehyde/ketone at room temperature in tetrahydrofuran for 10~25 min to give diindolylmethane derivatives in 86%~96% yields. The catalyst zirconocene bis(perfluorooctanesulfonate)s can be reused 6 times, and the conversion rate is still as high as 90%. This reaction does not require strict anhydrous conditions. This procedure provides a new and efficient way for preparing diindolylmethane derivatives.

Key words: zirconocene bis(perfluorooctanesulfonate)s, catalysis, synthesis, diindolylmethane derivatives