Chinese Journal of Organic Chemistry ›› 2024, Vol. 44 ›› Issue (2): 631-637.DOI: 10.6023/cjoc202309021 Previous Articles     Next Articles



李思达a,b,c, 崔鑫a, 舒兴中b,*(), 吴立朋a,d,*()   

  1. a 中国科学院兰州化学物理研究所 羰基合成与选择氧化国家重点实验室 兰州 730000
    b 兰州大学化学化工学院 功能有机分子化学国家重点实验室 兰州 730000
    c 中国科学院大学 北京 100049
    d 杭州师范大学材料与化学化工学院 有机硅化学及材料技术教育部重点实验室 杭州 311121
  • 收稿日期:2023-09-21 修回日期:2023-10-04 发布日期:2023-10-12
  • 作者简介:
  • 基金资助:
    国家自然科学基金(22271295); 及甘肃省自然科学基金重点(23JRRA606)

Titanium-Catalyzed Synthesis of 1,1-Diborylalkanes from Aryl Alkenes

Sida Lia,b,c, Xin Cuia, Xing-Zhong Shub(), Lipeng Wua,d()   

  1. a State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000
    b State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000
    c University of Chinese Academy of Sciences, Beijing 100049
    d Key Laboratory of Organosilicon Chemistry and Material Technology, Ministry of Education, College of Material Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou 311121
  • Received:2023-09-21 Revised:2023-10-04 Published:2023-10-12
  • Contact: E-mail:;
  • About author:
    These authors contributed equally to this work.
  • Supported by:
    National Natural Science Foundation of China(22271295); Natural Science Foundation of Gansu Province Key Project(23JRRA606)

A milder and general atom-economical synthesis of 1,1-diborylalkanes from aryl alkenes with pinacolborane (HBpin) at room temperature is achieved. The key to success is using an earth-abundant titanium-based catalyst (Cp2TiCl2) with the help of lithium methoxide (MeOLi) as the activator. It is proposed that the in-situ formation of Ti-H species from Cp2TiCl2/MeOLi/HBpin system is the vital active species for the catalytic results.

Key words: titanium, alkene, 1,1-diboration, catalysis