Chin. J. Org. Chem. ›› 2017, Vol. 37 ›› Issue (7): 1714-1720.DOI: 10.6023/cjoc201702037 Previous Articles     Next Articles



韩恩健, 郭勇, 陈庆云   

  1. 中国科学院上海有机化学研究所 上海 200032
  • 收稿日期:2017-02-25 修回日期:2017-05-12 发布日期:2017-06-23
  • 通讯作者: 郭勇
  • 基金资助:


Copper-Mediated Addition Reactions to Styrenes with 1,1,1-Trifluoro-2,2-dichloroethane or 1,1,1-Trifluoro-2,2,2-tricholorethane

Han Enjian, Guo Yong, Chen Qingyun   

  1. Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032
  • Received:2017-02-25 Revised:2017-05-12 Published:2017-06-23
  • Contact: 10.6023/cjoc201702037
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos.21421002,21672239).

An efficient CuCl/bpy-mediated atom transfer radical addition reaction of styrenes with CF3CHCl2 and CF3CCl3 is developed. Bpy which was added to enhance the reducibility of copper was crucial for activating one inert C-Cl bond of CF3CHCl2 and CF3CCl3 to form single radical adducts.

Key words: HCFC, copper, radical, alkene