Chin. J. Org. Chem. ›› 2009, Vol. 29 ›› Issue (03): 441-443. Previous Articles     Next Articles

Reports

微波辐射下合成5-亚苄基假乙内酰硫脲

李艳伦a; 周建峰*,a,b ; 贡桂霞b; 朱凤霞a   

  1. (a淮阴师范学院化学系 江苏省低维材料化学重点建设实验室 淮安 223300)
    (b苏州大学化学化工学院 江苏省有机合成重点实验室 苏州 215123)
  • 收稿日期:2008-05-21 修回日期:2008-09-12 发布日期:2009-03-20
  • 通讯作者: 周建峰

Synthesis of 5-Benzylidene Pseudothiohydantoin under Microwave Irradiation

Li, Yanluna ; Zhou, Jianfeng*,a,b; Gong, Guixiab; Zhu, Fengxiaa   

  1. (a Jiangsu Key Laboratory for Chemistry of Low-dimensional Materials, Department of Chemistry,
    Huaiyin Teachers College, Huaian 223300)
    (b Key Laboratory of Organic Synthesis of Jiangsu Province, School of Chemistry and Chemical Engineering,
    Suzhou University, Suzhou 215123)
  • Received:2008-05-21 Revised:2008-09-12 Published:2009-03-20
  • Contact: Zhou, Jianfeng

A series of 5-benzylidene pseudothiohydantoin derivatives were synthesized by the cross aldol condensation of benzaldehydes with pseudothiohydantoin in sodium acetate/acetic acid under microwave irradiation. The reactions were completed in 10 min with 63%~91% yields, easy work-up and environmental benignity.

Key words: pseudothiohydantoin, aromatic aldehyde, microwave irradiation, 5-benzylidene pseudothiohydantoin