Synthesis, Characterization and Bioactivity of 1-Nitrogenous Heterocyclic-2-(6-methoxynaphth-2-yl)propan-2-ol

Chin. J. Org. Chem. ›› 2009, Vol. 29 ›› Issue (06): 989-992. Previous Articles Next Articles

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1-氮杂环-2-(6-甲氧基萘-2-基)丙-2-醇的合成、表征与生物活性

陈平^a; 王宇^b,c ; 胡艾希^*,b ; 张建宇^b,c ; 于正英^b ; 欧晓明^c

(a长沙理工大学化学与生物工程学院长沙 410004)
(b湖南大学化学化工学院长沙 410082)
(c国家农药创制工程技术研究中心长沙 410007)

收稿日期:2008-10-24 修回日期:2008-12-10 发布日期:2009-06-20
通讯作者: 胡艾希

Synthesis, Characterization and Bioactivity of 1-Nitrogenous Heterocyclic-2-(6-methoxynaphth-2-yl)propan-2-ol

Chen, Ping^a ; Wang, Yu _^b,c ; Hu, Aixi^*,b ; Zhang, Jianyu ^b,c ;
Yu, Zhengying^b; Ou, Xiaoming^c

(a College of Chemical and Biological Engineering, Changsha University of Science and Technology, Changsha 410004)
(b College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082)
(c National Engineering Research Center for Agrochemicals, Changsha 410007)

Received:2008-10-24 Revised:2008-12-10 Published:2009-06-20
Contact: Hu, Aixi

Abstract

Four novel 1-nitrogenous heterocyclic-2-(6-methoxynaphth-2-yl)propan-2-ols were synthesized by epoxidation and ring-opening reaction from 1-(6-methoxynaphth-2-yl)ethanones. Their structures were established by MS and 1H NMR data. Proton assignment of naphthyl was determined by analyzing coupling fission constants on the naphthyl of the target compound. The preliminary bioassays indicated that some compounds showed fungicidal activities.

Key words: synthesis, characterization, bioactivi, nitrogenous heterocycle

Cite this article

Chen, Ping^a ; Wang, Yu _^b,c ; Hu, Aixi^*,b ; Zhang, Jianyu ^b,c ;
Yu, Zhengying^b; Ou, Xiaoming^c
. Synthesis, Characterization and Bioactivity of 1-Nitrogenous Heterocyclic-2-(6-methoxynaphth-2-yl)propan-2-ol[J]. Chin. J. Org. Chem., 2009, 29(06): 989-992.

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1-氮杂环-2-(6-甲氧基萘-2-基)丙-2-醇的合成、表征与生物活性

Synthesis, Characterization and Bioactivity of 1-Nitrogenous Heterocyclic-2-(6-methoxynaphth-2-yl)propan-2-ol

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