Copper catalyzed coupling reactions of Grignard reagents with α,ω -dibromoalkanes

Abstract

The cross mono-coupling reactions of Grignard reagents with a,w-dibromoalkanes catalyzed by some copper salt complexes were studied. The use of N,N,N',N'-tetramethylethylenediamine could improve the reaction conditions and expand the scope of this method, and a series of long chain bromoalkanes (C18-30) were prepared

Key words: REACTION MECHANISM, INFRARED SPECTROPHOTOMETRY, CATALYST, COPPER COMPLEX, BROMOHYDROCARBON, TETRAHYDROFURAN, PROTON MAGNETIC RESONANCE SPECTROMETRY, ALKANE P, GRIGNARD REAGENT, COUPLING REACTION

CLC Number:

O621

Cite this article

ZHANG HANCHENG;ZHANG JIAWANG;GUO QIZHEN. Copper catalyzed coupling reactions of Grignard reagents with α,ω -dibromoalkanes[J]. Chin. J. Org. Chem., 1988, 8(1): 67-70.

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铜催化下格氏试剂与α,ω-二溴代烷的偶合反应