Palladium-catalyzed cyclization and cross-coupling reactions of acetylenic alkoxides

Chin. J. Org. Chem. ›› 1993, Vol. 13 ›› Issue (3): 297-298. Previous Articles Next Articles

Original Articles

钯催化的乙炔烷氧化物的环化和交叉偶合反应

罗芬台;WANG REN-TZONG;INESSA SCHREUDR

中央研究院化学研究所

发布日期:1993-06-25

Palladium-catalyzed cyclization and cross-coupling reactions of acetylenic alkoxides

LUO FENTAI;WANG REN-TZONG;INESSA SCHREUDR

Published:1993-06-25

Abstract

Pd(OAc)2 or PdCl2 catalyzed the cyclization and cross-coupling of acetylenic alkyl or aryl alkoxides [e.g., alkoxides derived from 2-HOC6H4CH2CYCH, HO(CH2)3CYCH (I)] with organic halides (e.g., PhI, 2-iodothiophene) to give a-alkylidene cyclic ethers. E.g., treating I in THF with BuLi, then with Pd(OAc)2/PPh3, followed by PhI, gave furan II stereoselectively.

Key words: FURAN P, ALKYNE P, CYCLIZATION, METAL CATALYST, PALLADIUM, ALCOHOL, PYRANE P

CLC Number:

O621

Cite this article

LUO FENTAI;WANG REN-TZONG;INESSA SCHREUDR. Palladium-catalyzed cyclization and cross-coupling reactions of acetylenic alkoxides[J]. Chin. J. Org. Chem., 1993, 13(3): 297-298.

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钯催化的乙炔烷氧化物的环化和交叉偶合反应

Palladium-catalyzed cyclization and cross-coupling reactions of acetylenic alkoxides

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