Chinese Journal of Organic Chemistry ›› 2021, Vol. 41 ›› Issue (7): 2743-2749.DOI: 10.6023/cjoc202101015 Previous Articles Next Articles
ARTICLES
赵雯辛a, 黄孟君b, 李胜男a, 刘玉静a, 刘中秋a,*(), 应安国a,b,*()
收稿日期:
2021-01-08
修回日期:
2021-02-04
发布日期:
2021-04-16
通讯作者:
刘中秋, 应安国
基金资助:
Wenxin Zhaoa, Mengjun Huangb, Shengnan Lia, Yujing Liua, Zhongqiu Liua(), An'guo Yinga,b()
Received:
2021-01-08
Revised:
2021-02-04
Published:
2021-04-16
Contact:
Zhongqiu Liu, An'guo Ying
Supported by:
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Wenxin Zhao, Mengjun Huang, Shengnan Li, Yujing Liu, Zhongqiu Liu, An'guo Ying. One-Pot Synthesis of 3,4-Dihydropyrimidine-2-one Derivatives via Biginelli Reactions Catalyzed by SnCl2@MNPs[J]. Chinese Journal of Organic Chemistry, 2021, 41(7): 2743-2749.
Entry | 4 | R1 | X | R2 | Yield/% |
---|---|---|---|---|---|
1 | 4a | EtO | O | C6H5 | 96 |
2 | 4b | EtO | O | 3-NO2-C6H4 | 87 |
3 | 4c | EtO | O | 2-Cl-C6H4 | 87 |
4 | 4d | EtO | O | 2-CH3O-C6H4 | 95 |
5 | 4e | EtO | O | 4-CH3O-C6H4 | 88 |
6 | 4f | EtO | O | 4-CH3-C6H4 | 87 |
7 | 4g | EtO | O | 4-(CH3)2N-C6H4 | 92 |
8 | 4h | EtO | O | 3,4-(CH3O)2-C6H3 | 89 |
9 | 4i | EtO | O | 3-CH3O-4-HO-C6H3 | 90 |
10 | 4j | EtO | O | C4H3S | 93 |
11 | 4k | EtO | O | C10H7 | 88 |
12 | 4l | MeO | S | C6H5 | 78 |
13 | 4m | MeO | O | C6H5 | 94 |
14 | 4n | Me | O | C6H5 | 95 |
15 | 4o | Ph | O | C6H5 | 82 |
Entry | 4 | R1 | X | R2 | Yield/% |
---|---|---|---|---|---|
1 | 4a | EtO | O | C6H5 | 96 |
2 | 4b | EtO | O | 3-NO2-C6H4 | 87 |
3 | 4c | EtO | O | 2-Cl-C6H4 | 87 |
4 | 4d | EtO | O | 2-CH3O-C6H4 | 95 |
5 | 4e | EtO | O | 4-CH3O-C6H4 | 88 |
6 | 4f | EtO | O | 4-CH3-C6H4 | 87 |
7 | 4g | EtO | O | 4-(CH3)2N-C6H4 | 92 |
8 | 4h | EtO | O | 3,4-(CH3O)2-C6H3 | 89 |
9 | 4i | EtO | O | 3-CH3O-4-HO-C6H3 | 90 |
10 | 4j | EtO | O | C4H3S | 93 |
11 | 4k | EtO | O | C10H7 | 88 |
12 | 4l | MeO | S | C6H5 | 78 |
13 | 4m | MeO | O | C6H5 | 94 |
14 | 4n | Me | O | C6H5 | 95 |
15 | 4o | Ph | O | C6H5 | 82 |
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