有机化学 ›› 2020, Vol. 40 ›› Issue (6): 1689-1696.DOI: 10.6023/cjoc201912006 上一篇    下一篇

所属专题: 有机硅化学合辑

研究论文

三氟甲基酰腙与烯丙基硅或烯丙基硼试剂的烯丙基化反应研究

虎永琴, 黄丹凤, 王克虎, 赵转霞, 赵芳霞, 徐炜刚, 胡雨来   

  1. 西北师范大学化学化工学院 兰州 730070
  • 收稿日期:2019-12-04 修回日期:2020-02-17 发布日期:2020-03-04
  • 通讯作者: 黄丹凤, 胡雨来 E-mail:huyl@nwnu.edu.cn;huangdf@nwnu.edu.cn
  • 基金资助:
    国家自然科学基金(No.21662030)资助项目.

Study on Allylation Reactions of Trifluoromethylated Acylhydrazones with Allylsilanes or Allylboronates

Hu Yongqin, Huang Danfeng, Wang Kehu, Zhao Zhuanxia, Zhao Fangxia, Xu Weigang, Hu Yulai   

  1. College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070
  • Received:2019-12-04 Revised:2020-02-17 Published:2020-03-04
  • Supported by:
    Project supported by the National Natural Science Foundation of China (No. 21662030).

探索了在路易斯酸存在下,三氟甲基酰腙与烯丙基三甲基硅烷或烯丙基硼酸频哪醇酯的烯丙基化反应,高产率地获得了一系列三氟甲基取代的高烯丙基酰肼类化合物.研究结果表明,在三氟甲基酰腙的烯丙基化反应中,烯丙基硼酸频哪醇酯比烯丙基三甲基硅烷的活性高.

关键词: 三氟甲基酰腙, 烯丙基三甲基硅烷, 烯丙基硼酸频哪醇酯, 烯丙基化, 三氟甲基高烯丙基酰肼

Allylation reactions of trifluoromethylated acylhydrazones with allyltrimethylsilane or pinacolyl allylboronate were found to proceed smoothly in the presence of Lewis acid to afford a series of trifluoromethylated homoallylic N-acylhydrazines with high yields. The results showed that the activity of pinacolyl allylboronate was higher than that of allyltrimethylsilane in allylation of trifluoromethylated acylhydrazones.

Key words: trifluoromethylated acylhydrazone, allyltrimethylsilane, pinacolyl allylboronate, allylation, trifluoromethylated homoallylic N-acylhydrazine