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有机化学 ›› 2001, Vol. 21 ›› Issue (1): 1-7. 上一篇 下一篇
研究论文
丁明武;刘钊杰
发布日期:
Ding Mingwu;Liu Zhaojie
Published:
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综述了最近几年氮杂Wittig反应的研究进展,包括分子间氮杂Wittig反应、分子内氮杂wittig反应及串联的氮杂Wittig反应。讨论了氮杂Wittig反应在一些含氮杂环、稠杂环及天然产物合成中的应用。
关键词: 有机合成, 维蒂希反应, 稠环化合物, 氮杂环化合物, 分子间反应, 分子内反应
Recent advances in aza-Wittig reaction, including intermolecular, intramolecular and tandem ones, are reviewed. The application of the aza-Wittig reactions in synthesis of some N-heterocycles, fused heterocycles and natural products are also discussed. Some N- containing compounds not easily accessible by other methods were prepared by intermolecular aza-Wittig reactions under mild neutral conditions. The effcient intramolecular aza-Wittig reaction was also successively utilized in synthesis of five to eight-membered heterocycles, including some optically active natural compounds. Many heterocycles, fused heterocycles and natural compounds were prepared via the versatile tandem aza-Wittig reaction, such as tandem aza- Wittig/heterocumulene- mediated annulation, three component tandem aza- Wittig reaction, tandem aza-Wittig/electrocyclic ring closure, tandem aza-Wittig/ hetero-Diels-Alder closure and tandem aza-Wittig reaction utilizing bis-iminophosphorane.
Key words: ORGANIC SYNTHESIS, WITTIG REACTION, FUSED RING COMPOUNDS, NITROGEN HETEROCYCLICS, INTERNAL MOLECULAR REACTION
中图分类号:
O621
丁明武,刘钊杰. 氮杂Wittig反应的最近进展[J]. 有机化学, 2001, 21(1): 1-7.
Ding Mingwu;Liu Zhaojie. Recent advances in Aza-Wittig reaction[J]. Chin. J. Org. Chem., 2001, 21(1): 1-7.
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