有机化学 ›› 2017, Vol. 37 ›› Issue (3): 566-576.DOI: 10.6023/cjoc201610011 上一篇    下一篇

所属专题: 高被引论文合辑(2017-2018)

综述与进展

自由基引发的无过渡金属催化C-N构建研究进展

袁斯甜a, 王艳华a, 邱观音生b, 刘晋彪a   

  1. a 江西理工大学冶金与化学工程学院 赣州 341000;
    b 嘉兴学院生物与化学工程学院 嘉兴 314001
  • 收稿日期:2016-10-09 修回日期:2016-11-11 出版日期:2017-03-25 发布日期:2016-11-22
  • 通讯作者: 刘晋彪,E-mail:liujbgood@hotmail.com;邱观音生,E-mail:qiuguanyinsheng@mail.zjxu.edu.cn E-mail:liujbgood@hotmail.com;qiuguanyinsheng@mail.zjxu.edu.cn
  • 基金资助:

    国家自然科学基金(Nos.21502075,21502069)和浙江省自然科学基金(No.LQ15B020006)资助项目.

Recent Advances in Radical Initiated C-N Bond Formation under Transition Metal-Free Conditions

Yuan Sitiana, Wang Yanhuaa, Qiu Guanyinshengb, Liu Jinbiaoa   

  1. a School of Metallurgical and Chemical Engineering, Jiangxi University of Science and Technology, Ganzhou 341000;
    b College of Biological, Chemical Science and Engineering, Jiaxing University, Jiaxing 314001
  • Received:2016-10-09 Revised:2016-11-11 Online:2017-03-25 Published:2016-11-22
  • Contact: 10.6023/cjoc201610011 E-mail:liujbgood@hotmail.com;qiuguanyinsheng@mail.zjxu.edu.cn
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos. 21502075, 21502069) and the Natural Science Foundation of Zhejiang Province (No. LQ15B020006).

有机含氮化合物是一类极为重要的分子,广泛存在于有机合成化合物、天然产物及药物中.近年来,在无过渡金属催化下,自由基引发的C-H直接官能化反应已经引起化学家们的广泛关注.对基于自由基引发的无过渡金属催化体系,就不同杂化类型C-H键参与的C-N构建研究进展进行简要综述.

关键词: C-H键活化, C-N键, 自由基, 脱氢偶联

Nitrogen-containing compounds are extremely important because of their abundance in synthetic organic compounds, natural products and pharmaceutical agents. Recently, transition metal-free C-N bond-formation via radical procedures has attracted wide interest. The recent advances in C-N bond formation via C(sp3, sp2 or sp)-H bond activation under transition metal-free conditions are summarized.

Key words: C-H activation, C-N bond, radical, dehydrogenative coupling