有机化学 ›› 2018, Vol. 38 ›› Issue (7): 1626-1637.DOI: 10.6023/cjoc201801046 上一篇    下一篇

所属专题: 二氧化碳合辑

综述与进展

二氧化碳与亲核试剂反应的研究进展

徐佩, 汪顺义, 方毅, 纪顺俊   

  1. 苏州大学材料与化学化工学部和苏州纳米科技协同创新中心 江苏省有机合成重点实验室 苏州 215123
  • 收稿日期:2018-01-30 修回日期:2018-03-02 发布日期:2018-03-16
  • 通讯作者: 纪顺俊 E-mail:shunjun@suda.edu.cn
  • 基金资助:

    国家自然科学基金(Nos.21542015,21672157)和江苏省高校自然科学基金重大基础研究(No.16KJA150002)资助项目.

Research Progress on the Reaction of Carbon Dioxide with Nucleophiles

Xu Pei, Wang Shun-Yi, Fang Yi, Ji Shun-Jun   

  1. Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science & Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou 215123
  • Received:2018-01-30 Revised:2018-03-02 Published:2018-03-16
  • Contact: 10.6023/cjoc201801046 E-mail:shunjun@suda.edu.cn
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos. 21542015, 21672157), and the Major Basic Research Project of the Natural Science Foundation of the Jiangsu Higher Education Institutions (No. 16KJA150002).

二氧化碳作为绿色廉价的C1合成子有着重要的研究价值和工业应用前景.近年来,用二氧化碳合成环状氨基甲酸脂、喹唑啉-2,4-(1H,3H)-二酮、环状内酯等杂环化合物一直是研究热点.利用二氧化碳中碳原子具有缺电子的性质与亲核试剂反应就可以合成很多杂环化合物.主要总结了最近几年二氧化碳与以氮、氧或碳为亲核中心的亲核试剂发生分子间和分子内反应.

关键词: 二氧化碳, 亲核试剂, 亲电试剂, 氨基, 羟基, 碳负离子

Carbon dioxide as a green and cheap C1 synthon has significant research value and industrial application prospect. In recent years, using carbon dioxide to synthesize cyclic carbamates, quinazoline-2,4-(1H,3H)-diones, cyclic lactones and other heterocyclic compounds have been research hotspot. Many of the heterocyclic compounds can be synthesized by reacting the carbon atom in carbon dioxide with electron deficient with nucleophiles. This review focuses on the recent intermolecular and intramolecular reactions of carbon dioxide with nucleophiles centered around nitrogen, oxygen, or carbon.

Key words: carbon dioxide, nucleophiles, electrophiles, amino, hydroxyl, carbanion