Chin. J. Org. Chem. ›› 2013, Vol. 33 ›› Issue (02): 224-244.DOI: 10.6023/cjoc201208036 Previous Articles     Next Articles



代玲玲1, 崔胜峰1, Guri L. V. Damu1,2, 周成合1   

  1. 1 西南大学化学化工学院 重庆 400715;
    2 Postdoctoral fellow from Indian Institute of Chemical Technology (IICT), Hyderabad-500 607, India
  • 收稿日期:2012-08-31 修回日期:2012-11-05 发布日期:2012-11-14
  • 通讯作者: 周成合
  • 基金资助:

    国家自然科学基金(No. 21172181);外国青年学者研究基金(No. 81250110089);重庆市自然科学基金重点(No. CSTC2012jjB10026);高等学校博士学科点专项科研基金(No. SRFDP 20110182110007);中央高校基本科研业务费专项资金(Nos. XDJK2011D007, XDJK2012B026)资助项目.

Recent Advances in the Synthesis and Application of Tetrazoles

Dai Lingling1, Cui Shengfeng1, Damu Guri L. V.1,2, Zhou Chenghe1   

  1. 1 School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715;
    2 Postdoctoral fellow from Indian Institute of Chemical Technology (IICT), Hyderabad-500 607, India
  • Received:2012-08-31 Revised:2012-11-05 Published:2012-11-14
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21172181), the Research Fellowship for International Young Scientists from International (Regional) Cooperation and Exchange Program (No. 81250110089), the Key Program from Natural Science Foundation of Chongqing City (No. CSTC2012jjB10026), the Specialized Research Fund for the Doctoral Program of Higher Education of China (No. SRFDP 20110182110007) and the Fundamental Research Funds for the Central Universities (Nos. XDJK2011D007, XDJK2012B026).

Tetrazole is an important five-membered aromatic heterocycle with poly-nitrogen electron-rich planar structural feature. This unique structure endows tetrazole derivatives as drugs, explosives, functional materials etc. to exhibit wide potential applications in medicinal, agrochemical, material science and so on. Relevant researches have been becoming active and some important achievements have been made. Based our work on azoles and referring to other literature in recent 5 years, this review systematically summarized the recent advances in the synthesis of tetrazole compounds and their application researches as medicinal drugs, agrochemicals and materials.

Key words: tetrazole, antihypertensive, antibacterial, antiviral, herbicide, energetic materials, catalyst