Chinese Journal of Organic Chemistry ›› 2022, Vol. 42 ›› Issue (1): 1-15.DOI: 10.6023/cjoc202109002 Previous Articles     Next Articles



徐磊, 王方, 陈凡, 朱圣卿*(), 储玲玲*()   

  1. 东华大学化学化工与生物工程学院 先进低维材料中心 上海 201620
  • 发布日期:2022-01-24
  • 通讯作者: 朱圣卿, 储玲玲
  • 基金资助:
    国家自然科学基金(21991123); 国家自然科学基金(21971036); 国家自然科学基金(21901036); 中央高校基本科研业务费专项资金和东华大学研究生创新基金(CUSF-DH-D-2020057)

Recent Advances in Photoredox/Nickel Dual-Catalyzed Difunctionalization of Alkenes and Alkynes

Lei Xu, Fang Wang, Fan Chen, Shengqing Zhu(), Lingling Chu()   

  1. Center for Advanced Low-Dimension Materials, College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620
  • Published:2022-01-24
  • Contact: Shengqing Zhu, Lingling Chu
  • Supported by:
    National Natural Science Foundation of China(21991123); National Natural Science Foundation of China(21971036); National Natural Science Foundation of China(21901036); Fundamental Research Funds for the Central Universities and the Graduate Student Innovation Fund of Donghua University(CUSF-DH-D-2020057)

The merger of visible-light photoredox catalysis and nickel catalysis makes it possible to forge challenging chemical bonds under mild conditions. Nevertheless, most of these transformations only construct a single carbon-carbon bond or carbon-heteroatom bond in one operation. In recent years, photoredox/nickel dual catalysis has attracted widespread attention in the field of catalytic difunctionalization of alkenes and alkynes. The synergistic cascade mode enables the construction of multiple chemical bonds in one single pot, providing a mild, efficient and selective protocol for the rapid assembly of complex structural motifs. The latest progress in the photoredox/nickel dual-catalyzed difunctionalization reactions of olefins and alkynes is summarized.

Key words: photoredox catalysis, nickel catalysis, synergistic catalysis, alkene, alkyne, difunctionalization