有机化学 ›› 2013, Vol. 33 ›› Issue (04): 693-703.DOI: 10.6023/cjoc201303005 上一篇    下一篇

综述与进展

钯催化的有机硼化物与羧酸衍生物的交叉偶联反应

杨军, 邓敏智, 于涛   

  1. 中国科学院上海有机化学研究所 上海 200032
  • 收稿日期:2013-03-04 修回日期:2013-04-05 发布日期:2013-04-07
  • 通讯作者: 杨军, 邓敏智 E-mail:yangj@sioc.ac.cn; dengmz@sioc.ac.cn
  • 基金资助:

    国家自然科学基金(Nos. 20802088, 91017006, 90917017)资助项目.

Palladium-Catalyzed Cross-Coupling Reaction of Organoboron Compounds with Carboxylic Derivatives

Yang Jun, Deng Minzhi, Yu Tao   

  1. Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032
  • Received:2013-03-04 Revised:2013-04-05 Published:2013-04-07
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos. 20802088, 91017006, 90917017).

钯催化的交叉偶联反应是构建C—C键的常用方法, 近年来, 钯催化的有机硼化物与羧酸衍生物的交叉偶联反应已成为偶联反应研究中的热点. 本文综述了最近十几年多种有机硼化物与酰氯、酸酐、羧酸、氯甲酸衍生物、羧酸活性酯、羧酸硫酯的交叉偶联反应研究进展, 并对该反应在有机合成中的应用进行了讨论.

关键词: 羧酸衍生物, 交叉偶联, 钯催化剂

Palladium-catalyzed cross-coupling reaction has emerged as an important strategy to the formation of C—C bond. Recently, palladium-catalyzed cross-coupling reaction between organoboron compounds and carboxylic derivatives has become a hotspot of organic chemistry. In this paper, recent researches of organoboron compounds with acyl chlorides, acid anhydrides, carboxylic acids, chloroformic derivatives, carboxylic esters and thiol esters in Suzuki cross-coupling are summarized, and the examples of these reactions in synthesis are also discussed.

Key words: carboxylic derivatives, Suzuki cross-coupling, palladium catalyst