铑(III)催化氧化锍叶立德和重氮化合物环化偶联反应

doi:10.6023/cjoc202405011

摘要/Abstract

本工作报道了氧化还原中性条件下过渡金属铑催化氧化锍叶立德C-H 键活化与两类环状重氮化合物发生环化反应,分别合成了结构多样性的稠环和螺环。该反应通过螯合辅助的C-H活化、卡宾插入以及随后的分子内[3+3]环化或者[4+1]螺环化反应进行。

The Rh(III)-catalyzed C-H functionalization of sulfoxonium ylides and successively annulation with two classes of cyclic diazo compounds has been realized, affording structurally diverse fused-ring or spirocyclic compounds under redox-neutral conditions. The reaction proceeds via successive chelation-assisted C-H activation, carbene insertion, and intramolecular [3+3]/[4+1] annulation processess.

Key words: Rhodium catalysis, Sulfoxonium ylides, C-H activation, Diazo compounds, Annulation

引用此文

杨帆, 范小梦, 姚雪婧, 米瑞杰, 于松杰, 李兴伟, 肖建. 铑(III)催化氧化锍叶立德和重氮化合物环化偶联反应[J]. 有机化学, doi: 10.6023/cjoc202405011.

Fan Yang, Xiaomeng Fan, Xuejing Yao, Ruijie Mi, Songjie Yu, Xingwei Li, Jian Xiao. Rhodium(III)-Catalyzed Annulative Coupling between Sulfoxonium Ylides and Diazo Compounds via C-H Activation[J]. Chinese Journal of Organic Chemistry, doi: 10.6023/cjoc202405011.

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