硫鎓盐参与的有机合成反应研究进展

doi:10.6023/cjoc202603036

摘要/Abstract

硫鎓盐是一类由三个取代基连接于硫原子带正电的有机硫化合物。由于中心硫原子携带正电荷,硫鎓盐表现出独特的电性特征和优异的反应活性,能够参与多种类型的有机反应。近年来,随着有机化学方法学的发展,硫鎓盐在交叉偶联反应、自由基转化、官能团化以及复杂分子构建等领域展现出重要应用价值。本文系统总结了近年硫鎓盐在高效有机合成新方法以及应用研究方面的最新进展,重点介绍其在不同类型有机反应中的应用,并对部分反应机理进行讨论,以期为硫鎓盐在有机合成及相关领域的进一步研究提供参考。

关键词: 硫化学, 硫鎓盐, 有机合成, 反应机理, 应用

Sulfonium salts are a class of positively charged organosulfur compounds in which three substituents are bonded to a sulfur atom. Owing to the positively charged sulfur center, sulfonium salts exhibit unique electronic properties and high electrophilic reactivity, enabling diverse chemical transformations. In recent years, with the rapid development of synthetic methodologies, sulfonium salts have emerged as versatile intermediates in organic synthesis and have been widely applied in cross-coupling reactions, radical transformations, functional group modifications, and the construction of complex molecules. This review summarizes recent advances in the synthesis and strategic applications of sulfonium salts in organic synthesis, highlighting their strategic applications in diverse organic reactions. Representative reaction mechanisms are also discussed to provide insights for the further development of sulfonium-salt-mediated transformations.

Key words: sulfur chemistry, sulfonium salts, organic synthesis, reaction mechanisms, applications

引用此文

王丽君, 张钰, 芦阳, 王江. 硫鎓盐参与的有机合成反应研究进展[J]. 有机化学, doi: 10.6023/cjoc202603036.

Lijun Wang, Yu Zhang, Yang Lu, Jiang Wang. Recent Advances in Organic Synthetic Reactions Involving Sulfonium Salts[J]. Chinese Journal of Organic Chemistry, doi: 10.6023/cjoc202603036.

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