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有机化学
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有机化学 ›› 2009, Vol. 29 ›› Issue (02): 229-233. 上一篇    下一篇

研究论文

Pd/C催化下汉斯酯1,4-二氢吡啶还原芳香叠氮化合物、芳香硝基 化合物以及碳碳双键的反应研究

牛秀琴 ; 刘振刚 ; 于 炜*; 吴隆民   

  1. (兰州大学功能有机分子化学国家重点实验室 兰州 730000)
  • 收稿日期:2008-06-04 修回日期:2008-08-13 发布日期:2009-02-20
  • 通讯作者: 于 炜

Pd/C-Catalyzed Transfer Hydrogenation with Hantzsch Ester 1,4-Dihydropyridine for the Reduction of Aromatic Azides, Aromatic Nitro Compounds and Olefins

Niu, Xiuqin; Liu, Zhengang; Yu, Wei* ; Wu, Longmin   

  1. (State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000)
  • Received:2008-06-04 Revised:2008-08-13 Published:2009-02-20
  • Contact: Yu, Wei

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被引次数

10 | 2

汉斯酯1,4-二氢吡啶(HEH)在Pd/C催化下可以将取代的芳香叠氮化合物还原为相应的取代苯胺, 反应具有很好的选择性. 该方法也可以用于芳香硝基化合物的还原. 对于Pd/C催化下汉斯酯1,4-二氢吡啶还原碳碳双键的可行性, 论文中也进行了初步的探讨.

关键词: 汉斯酯1,4-二氢吡啶, 芳香叠氮化合物, 还原, 芳香硝基化合物, Pd/C

The Pd/C-catalyzed transfer hydrogenation with Hantzsch ester 1,4-dihydropyridine (HEH) provides an efficient protocol for the selective reduction of aromatic azides to the corresponding amines. The method is advantageous in terms of high yield and high selectivity. The reduction of aromatic nitro compounds can also be achieved with the method. In addition, the reagent combination of HEH-Pd/C is also effective for the reduction of conjugated olefins.

Key words: aromatic azide, Hantzsch ester 1,4-dihydropyridine, aromatic nitro compound, reduction, Pd/C