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有机化学
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有机化学 ›› 2007, Vol. 27 ›› Issue (06): 783-785. 上一篇    下一篇

研究简报

天然产物海洋联烯Xyloallenoid F的全合成

毛魏魏a，王三永*,b,c，李春荣c，杨定乔*,a，林永成b   

  1. (a华南师范大学化学与环境学院 广州 510006)
    (b中山大学化学与化学工程学院 广州 510275)
    (c广东省食品工业研究所 广州 510308)
  • 收稿日期:2006-09-11 修回日期:2006-10-18 发布日期:2007-05-21
  • 通讯作者: 杨定乔

Total Synthesis of the Natural Product Marine Allenic Xyloallenoid F

MAO Wei-Weia, WANG San-Yong*,b,c, LI Chun-Rongc, YANG Ding-Qiao*,a
LIN Yong-Chengb   

  1. (a School of Chemistry and Environment, South China Normal University, Guangzhou 510006)
    (b School of Chemistry and Chemical Engineering, Zhongshan University, Guangzhou 510275)
    (c Guangdong Institute of Food Industry, Guangzhou 510308)
  • Received:2006-09-11 Revised:2006-10-18 Published:2007-05-21
  • Contact: YANG Ding-Qiao

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被引次数

5 | 1

以丙炔醇为原料, 经Mannich反应、还原、溴化、Williamson合成法等共七步反应, 首次合成了从海洋真菌中分离的天然产物联烯Xyloallenoid F, 总收率25.4%, 目标化合物经IR, 1H NMR, 13C NMR, MS和元素分析进行测定和结构表征.

关键词: 全合成, Xyloallenoid F, 联烯化合物

Xyloallenoid F, which was isolated from marine fungus, was totally synthesized for the first time from starting material 2-propynol via seven-step reaction such as Mannich reaction, reduction, bromination and Williamson reaction etc. The overall yield was 25.4%. The target compound was confirmed by IR, 1H NMR, 13C NMR, MS spectra and elemental analysis.

Key words: total synthesis, xyloallenoid F, allenic compound