关键词: 区域选择性, 核苷羧酸酯, 酶促酰化

Nucleoside carboxylates are a group of compounds which have been found important applications in nucleoside chemistry, organic synthesis and medicinal chemistry. Recently, their enzymatic synthesis has attracted much attention due to the high efficiency, high regioselectivity and environmental friendliness of enzymatic processes. The advances achieved in this area in recent years are reviewed in this paper.

Key words: regioselectivity, enzymatic acylation, nucleoside carboxylate